RTN4R and LINGO1

Number of citations of the paper that reports this interaction (PubMedID 14966521)
220

Data Source:
HPRD (in vivo, in vitro)

		RTN4R	LINGO1
Description		reticulon 4 receptor	leucine rich repeat and Ig domain containing 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Anchored Component Of External Side Of Plasma Membrane Neuron Projection Neuronal Cell Body Dendritic Shaft Perikaryon Axonal Growth Cone Membrane Raft Extracellular Exosome Presynapse Glutamatergic Synapse	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix
	Molecular Function	Protein Binding Heparin Binding Chondroitin Sulfate Binding Signaling Receptor Activity Neuregulin Receptor Activity Protein-containing Complex Binding Ganglioside GM1 Binding Ganglioside GT1b Binding	Epidermal Growth Factor Receptor Binding Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Axonogenesis Negative Regulation Of Neuron Projection Development Corpus Callosum Development Neuronal Signal Transduction Negative Regulation Of Axon Extension Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of GTPase Activity Negative Regulation Of Axon Regeneration Negative Regulation Of Axonogenesis	Negative Regulation Of Axonogenesis
Pathways		Axonal growth inhibition (RHOA activation)	Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Obesity-related traits ( 23251661)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Essential tremor ( 19182806) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) Hemoglobin A1c levels ( 29403010) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neuroticism ( 27089181) Risky sexual behaviors (alcohol dependence interaction) ( 28990359)
Interacting Genes		6 interacting genes: LINGO1 MAG NGFR OMG RTN4 RTN4IP1	8 interacting genes: EFEMP2 FBXW7 GOLGA2 KRTAP4-12 NGFR RTN4R SPAG5 TRIM27
Entrez ID		65078	84894
HPRD ID		16123	14322
Ensembl ID		ENSG00000040608	ENSG00000169783
Uniprot IDs		Q9BZR6	Q96FE5
PDB IDs		1OZN 1P8T	2ID5 4OQT
Enriched GO Terms of Interacting Partners?
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