SHOX2 and TRIM29

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		SHOX2	TRIM29
Description		short stature homeobox 2	tripartite motif containing 29
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Lysosome Adherens Junction
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding	P53 Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Skeletal System Development Osteoblast Differentiation Positive Regulation Of Mesenchymal Cell Proliferation Chondrocyte Development Heart Valve Development Cardiac Atrium Morphogenesis Regulation Of Transcription By RNA Polymerase II Nervous System Development Heart Development Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Axonogenesis Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis Muscle Tissue Morphogenesis Regulation Of Branching Morphogenesis Of A Nerve	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971) Chronotype ( 30696823) Height ( 25429064 23563607 31562340) Idiopathic dilated cardiomyopathy ( 29495422) Lung cancer in never smokers ( 28604730) Monobrow ( 27182965) Neurociticism ( 29500382) Neuroticism ( 29255261) Pulse pressure ( 30224653)	Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Stroke (pediatric) ( 22990015)
Interacting Genes		3 interacting genes: CDK4 TRIM29 ZDHHC17	47 interacting genes: ATM CARD9 CDC34 CEP70 CRACR2A DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MYO15B POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM
Entrez ID		6474	23650
HPRD ID		03936	10280
Ensembl ID		ENSG00000168779	ENSG00000137699
Uniprot IDs		A6NLG4 O60902	A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134
PDB IDs			2CSV
Enriched GO Terms of Interacting Partners?
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