SH3GL1 and SEPTIN8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		SH3GL1	SEPTIN8
Description		SH3 domain containing GRB2 like 1, endophilin A2	septin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Podosome Cytoplasm Cytosol Cell Junction Early Endosome Membrane Cell Projection Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Presynapse Glutamatergic Synapse Postsynaptic Density, Intracellular Component	Septin Ring Microtubule Cytoskeleton Cell Junction Axon Synaptic Vesicle Membrane Septin Complex Cell Division Site Presynapse
	Molecular Function	Protein Binding Protein C-terminus Binding Lipid Binding SH3 Domain Binding Phosphatase Binding Beta-1 Adrenergic Receptor Binding Identical Protein Binding Ion Channel Binding Cadherin Binding GTPase Binding	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Signal Transduction Central Nervous System Development Synaptic Vesicle Uncoating Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Endocytosis	Cellular Protein Localization Regulation Of SNARE Complex Assembly Cytoskeleton-dependent Cytokinesis
Pathways		EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs
Diseases
GWAS
Interacting Genes		27 interacting genes: ARHGAP8 AXIN1 B3GAT1 CREBBP DNM1 DNM1L DPPA4 DPYSL4 FAM102A FBXO32 GPKOW ITCH ITSN2 LRRK2 MAL2 MTA1 PDCD6IP PML PTPRO SEPTIN8 SH2D4A SH3D19 SH3GL3 SYNJ1 VIM VPS37C YWHAZ	11 interacting genes: A2M CDK14 ESR1 JADE1 KMT2B PPHLN1 SEPTIN4 SEPTIN5 SH3GL1 SH3GL3 SPTBN1
Entrez ID		6455	23176
HPRD ID		03462	12228
Ensembl ID		ENSG00000141985	ENSG00000164402
Uniprot IDs		Q6FGM0 Q99961	A6NFQ9 B7ZVZ1 Q92599
PDB IDs
Enriched GO Terms of Interacting Partners?
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