BLMH and TRIO

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BLMH	TRIO
Description		bleomycin hydrolase	trio Rho guanine nucleotide exchange factor
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Cytosol Cell Projection
	Molecular Function	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity Identical Protein Binding	Protein Serine/threonine Kinase Activity Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding
	Biological Process	Protein Polyubiquitination Proteolysis Response To Toxic Substance Response To Drug Homocysteine Catabolic Process	Protein Phosphorylation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Axon Guidance Central Nervous System Development Positive Regulation Of Apoptotic Process Negative Regulation Of Fat Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	NRAGE signals death through JNK Rho GTPase cycle G alpha (q) signalling events G alpha (12/13) signalling events DCC mediated attractive signaling DCC mediated attractive signaling
Drugs
Diseases
GWAS			Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel) ( 24025145) Antidepressant treatment resistance (number of drugs prescribed) ( 30700811) Asthma (childhood onset) ( 31036433) Electroencephalogram traits ( 25387704) High density lipoprotein cholesterol levels ( 30498476) Intake of total sugars ( 31005972) Major depressive disorder ( 27777418) Paclitaxel-induced neuropathy ( 23776197) Waist circumference ( 28552196)
Interacting Genes		14 interacting genes: AP1M2 APP CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NUDT12 PDPK1 RNF32 RPL11 RPL29 TRIO UBE2I	11 interacting genes: BLMH CDC5L DISC1 EXOC1 FLNA ITSN2 MAPRE1 PTK2 PTPRF RAC1 RHOA
Entrez ID		642	7204
HPRD ID		03870	03537
Ensembl ID		ENSG00000108578	ENSG00000038382
Uniprot IDs		Q13867	O75962
PDB IDs		1CB5 2CB5	1NTY 2NZ8 6D8Z
Enriched GO Terms of Interacting Partners?
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