SELPLG and SELE

Number of citations of the paper that reports this interaction (PubMedID 8621728)
60

Data Source:
HPRD (in vivo, in vitro)

		SELPLG	SELE
Description		selectin P ligand	selectin E
Image
GO Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Caveola Clathrin-coated Pit Cortical Cytoskeleton Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Sialic Acid Binding Phospholipase Binding Metal Ion Binding Oligosaccharide Binding
	Biological Process	Cell Adhesion Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Positive Regulation Of Receptor Internalization Leukocyte Migration Involved In Inflammatory Response Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Activation Of Phospholipase C Activity Calcium-mediated Signaling Actin Filament-based Process Response To Lipopolysaccharide Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukocyte Migration Leukocyte Tethering Or Rolling Response To Interleukin-1 Positive Regulation Of Leukocyte Tethering Or Rolling
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs			Carvedilol N-acetyl-alpha-neuraminic acid
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Conduct disorder (symptom count) ( 20585324)	Blood protein levels ( 30072576) Inflammatory bowel disease ( 26192919)
Interacting Genes		15 interacting genes: BACE1 CIT CTSG ECSIT GALNT4 MAGEA1 MSN SELE SELL SELP SYK TNIP1 TPST1 TPST2 VCAN	14 interacting genes: ACTA2 ACTN2 CD44 FLNA GLG1 LGALS3BP PLCG1 PTK2 PTPN11 PXN SELL SELPLG SERPING1 VCL
Entrez ID		6404	6401
HPRD ID		02845	00566
Ensembl ID		ENSG00000110876	ENSG00000007908
Uniprot IDs		Q14242	P16581
PDB IDs		1G1S	1ESL 1G1T 1KJA 4C16 4CSY 6EYI 6EYJ 6EYK
Enriched GO Terms of Interacting Partners?
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