DMRTC2 and TXNRD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		DMRTC2	TXNRD1
Description		DMRT like family C2	thioredoxin reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin XY Body Cellular_component Nucleus	Fibrillar Center Cell Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Sequence-specific DNA Binding Metal Ion Binding	Thioredoxin-disulfide Reductase Activity Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatid Nucleus Elongation Sex Differentiation Biological_process Positive Regulation Of Histone H3-K9 Dimethylation Positive Regulation Of Histone H3-K9 Trimethylation	Mesoderm Formation Selenium Compound Metabolic Process Signal Transduction Cell Proliferation Nucleobase-containing Small Molecule Interconversion Regulation Of Lipid Metabolic Process Electron Transport Chain Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways			PPARA activates gene expression Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates Metabolism of ingested MeSeO2H into MeSeH Uptake and function of diphtheria toxin TP53 Regulates Metabolic Genes
Drugs			Arsenic trioxide Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate Flavin adenine dinucleotide Spermidine Fotemustine motexafin gadolinium PX-12
Diseases
GWAS			Blood protein levels ( 30072576) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Logical memory (delayed recall) in normal cognition ( 29274321) Toenail selenium levels ( 25343990)
Interacting Genes		2 interacting genes: IRF9 TXNRD1	10 interacting genes: DMRTC2 ESR1 ESR2 GLRX2 POU2F1 POU2F2 PPP1R16A THRA TXNDC17 TXNIP
Entrez ID		63946	7296
HPRD ID		16829	03068
Ensembl ID		ENSG00000142025	ENSG00000198431
Uniprot IDs		B4DX56 Q8IXT2	B7Z2S5 Q16881
PDB IDs			1W1C 2CFY 2J3N 2ZZ0 2ZZB 2ZZC 3QFA 3QFB
Enriched GO Terms of Interacting Partners?
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