RNF123 and EMD

Number of citations of the paper that reports this interaction (PubMedID 29676528)
4

Data Source:
BioGRID (enzymatic study)

		RNF123	EMD
Description		ring finger protein 123	emerin
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Membrane	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Microtubule Membrane Integral Component Of Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum
	Molecular Function	Ubiquitin-protein Transferase Activity Metal Ion Binding	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding
	Biological Process	Protein Ubiquitination Protein Deubiquitination Proteolysis Involved In Cellular Protein Catabolic Process	Muscle Contraction Mitotic Nuclear Envelope Reassembly Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Ub-specific processing proteases Antigen processing: Ubiquitination & Proteasome degradation	Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerisation of the Nuclear Lamina Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases			Emery-Dreifuss muscular dystrophy
GWAS		Age at first birth ( 27798627) Blood protein levels ( 28240269) Body mass index ( 26426971) Crohn's disease ( 28067908) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Household income ( 31844048) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908) Morning person ( 30696823) Multisite chronic pain ( 31194737) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 28067908)
Interacting Genes		14 interacting genes: CDKN1B EMD LMNA LMNB1 MTDH RB1 SMAD2 SMAD9 TMPO UBAC1 UBC UBE2D1 UBE2D2 UBE2W	45 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CEP70 COPS6 CREB3 CTNNBIP1 DPPA4 EFHC2 FATE1 GMCL1 KASH5 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX2 MTNR1A PAK5 PSME1 RNF123 SH3GL2 SH3GL3 SRC STX4 SYNE1 TRAF3IP3 TRIM42 VAPB VAV1 YTHDC1 ZFP64 ZNF165 ZNF232
Entrez ID		63891	2010
HPRD ID		11499	02309
Ensembl ID		ENSG00000164068	ENSG00000102119
Uniprot IDs		Q5XPI4	P50402
PDB IDs		2MA6	1JEI 2ODC 2ODG 6GHD
Enriched GO Terms of Interacting Partners?
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