CLEC11A and KITLG

Number of citations of the paper that reports this interaction (PubMedID 11920266)
17

Data Source:
HPRD (in vitro)

		CLEC11A	KITLG
Description		C-type lectin domain containing 11A	KIT ligand
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Extracellular Region Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Integral Component Of Membrane Lamellipodium Filopodium
	Molecular Function	Growth Factor Activity Carbohydrate Binding	Cytokine Activity Stem Cell Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Ossification Signal Transduction Positive Regulation Of Cell Proliferation	MAPK Cascade Ovarian Follicle Development Neural Crest Cell Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of Myeloid Leukocyte Differentiation Cell Adhesion Positive Regulation Of Cell Proliferation Male Gonad Development Negative Regulation Of Mast Cell Apoptotic Process Embryonic Hemopoiesis Ectopic Germ Cell Programmed Cell Death Positive Regulation Of MAP Kinase Activity Positive Regulation Of Melanocyte Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Mast Cell Proliferation Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways
Drugs
Diseases			Familial progressive hyperpigmentation
GWAS		Blood protein levels ( 30072576 29875488) Stem cell growth factor beta levels ( 27989323)	Blond vs non-blond hair color ( 26184321) Blond vs. brown hair color ( 17952075) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Brown vs. non-brown hair color ( 26184321) Hair color ( 23548203 29662168) Light vs. dark hair color ( 26184321) Nevus count ( 30429480) Red blood cell traits ( 23222517) Testicular cancer ( 19483682) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 19483681 28604728 28604732 23666239 23666240)
Interacting Genes		1 interacting genes: KITLG	8 interacting genes: CLEC11A CMA1 CSF2 EPOR FLT3LG KIT PIK3CD UBE2V1
Entrez ID		6320	4254
HPRD ID		05277	01698
Ensembl ID		ENSG00000105472	ENSG00000049130
Uniprot IDs		Q9Y240	A0A024RBC0 A0A024RBF5 P21583
PDB IDs			1EXZ 1SCF 2E9W
Enriched GO Terms of Interacting Partners?
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