SATB1 and MTA2

Number of citations of the paper that reports this interaction (PubMedID 12374985)
159

Data Source:
HPRD (in vivo)

		SATB1	MTA2
Description		SATB homeobox 1	metastasis associated 1 family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Heterochromatin Nuclear Matrix Nuclear Body PML Body	Histone Deacetylase Complex Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Membrane NuRD Complex Protein-containing Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Double-stranded DNA Binding Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding RNA Polymerase II Repressing Transcription Factor Binding Transcription Coactivator Activity Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Epidermis Development Viral Process Histone Methylation CD4-positive, Alpha-beta T Cell Differentiation CD8-positive, Alpha-beta T Cell Differentiation Activated T Cell Proliferation Reflex	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Chromatin Assembly Or Disassembly Regulation Of Fibroblast Migration Histone Deacetylation ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Apoptotic cleavage of cellular proteins SUMOylation of chromatin organization proteins	HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Chronic mucus hypersecretion ( 24714607) Familial lung adenocarcinoma ( 29924316) General risk tolerance (MTAG) ( 30643258) Itch intensity from mosquito bite ( 28199695) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Platelet count ( 22139419) Response to fenofibrate (HDL cholesterol levels) ( 27002377) SjÃ¶gren's syndrome ( 24097067)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		21 interacting genes: BAZ1A CASP6 CBX4 CHD3 CUX1 EP300 GATA3 HDAC1 KAT2B MTA2 PIAS1 PIAS3 PIAS4 POLR2J SIRT1 SMARCA5 SUMO1 SUMO1P1 TOPORS UBE2I UBR5	22 interacting genes: APPL1 APPL2 BCL11B ESR1 FKBP3 H3-4 HDAC2 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN SUMO2 TP53 TSC22D3 UBE3C YY1
Entrez ID		6304	9219
HPRD ID		03647	07233
Ensembl ID		ENSG00000182568	ENSG00000149480
Uniprot IDs		A0A024R2H1 Q01826	A0A024R534 O94776
PDB IDs		1YSE 2L1P 2MW8 2O49 2O4A 3NZL 3TUO
Enriched GO Terms of Interacting Partners?
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