RPS27 and MARS1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RPS27	MARS1
Description		ribosomal protein S27	methionyl-tRNA synthetase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ribosome Postsynaptic Density Cytosolic Small Ribosomal Subunit	Nucleolus Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding	TRNA Binding Methionine-tRNA Ligase Activity ATP Binding
	Biological Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation Cellular Response To Starvation RRNA Transcription Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Major pathway of rRNA processing in the nucleolus and cytosol Mitotic Prometaphase Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency EML4 and NUDC in mitotic spindle formation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: ACTN1 ACTN4 APC ENOPH1 ENTPD4 MARS1 NACAD NSG2 PPBP PTEN RTN4 SKIL TOM1 WDCP	8 interacting genes: CASK ESR1 HNRNPUL1 MAFK MAPK14 PPM1F RPS27 TNNT1
Entrez ID		6232	4141
HPRD ID		04744	08864
Ensembl ID		ENSG00000177954	ENSG00000166986
Uniprot IDs		P42677	P56192
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	2DJV 4BL7 4BVX 4BVY 5GL7 5GOY 5Y6L
Enriched GO Terms of Interacting Partners?
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