RPS6KB2 and HNRNPA1

Number of citations of the paper that reports this interaction (PubMedID 25324306)
16

Data Source:
BioGRID (enzymatic study)

		RPS6KB2	HNRNPA1
Description		ribosomal protein S6 kinase B2	heterogeneous nuclear ribonucleoprotein A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity ATP Binding Peptide Binding	Single-stranded DNA Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding MiRNA Binding Pre-mRNA Binding Telomeric Repeat-containing RNA Binding G-rich Strand Telomeric DNA Binding
	Biological Process	Translation Protein Phosphorylation Signal Transduction TOR Signaling Intracellular Signal Transduction Protein Kinase B Signaling Positive Regulation Of Translational Initiation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus Fibroblast Growth Factor Receptor Signaling Pathway Viral Process RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Glucose Starvation MRNA Transport Nuclear Export Import Into Nucleus Regulation Of RNA Metabolic Process Cellular Response To Sodium Arsenite
Pathways		AKT phosphorylates targets in the nucleus Constitutive Signaling by AKT1 E17K in Cancer	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: BTK COASY CSNK2B EEF2K EP300 FBXO25 FYN HNRNPA1 IKBKG KAT2B LRRK2 LYN MAPK8IP2 MTOR NEDD4L PDGFRB PDPK1 PRKCE RPS6 SRC SRPK1 SYK	40 interacting genes: ABHD16A APP BCL2L1 CLK1 ERG ESR1 FEN1 H3-4 H3C1 HIPK3 HMGA1 HNRNPH3 KHSRP NFKBIA NR0B2 NR3C1 PABPN1 PHYHIP PPIL1 PRKDC PRMT1 PRMT2 PRMT3 PRRC2A RNF14 RPL21 RPS6KB2 SAFB SNRNP200 SREK1 SRPK1 SRPK2 SUFU TFEC TNPO1 TRA2B TRAF6 TTF2 XIAP XRN1
Entrez ID		6199	3178
HPRD ID		10203	01242
Ensembl ID		ENSG00000175634	ENSG00000135486
Uniprot IDs		Q9UBS0	A0A024RAZ7 A0A024RB53 P09651
PDB IDs			1HA1 1L3K 1PGZ 1PO6 1U1K 1U1L 1U1M 1U1N 1U1O 1U1P 1U1Q 1U1R 1UP1 2H4M 2LYV 2UP1 4YOE 5MPG 5MPL 5ZGD 5ZGL 6BXX 6DCL 6J60
Enriched GO Terms of Interacting Partners?
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