RPL41 and NUPR1

Number of citations of the paper that reports this interaction (PubMedID 19650074)
16

Data Source:
BioGRID (two hybrid)

		RPL41	NUPR1
Description		ribosomal protein L41	nuclear protein 1, transcriptional regulator
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Cytosolic Large Ribosomal Subunit Polysomal Ribosome	Nucleus Nucleoplasm Cytoplasm Protein-DNA Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome MRNA 5'-UTR Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Acetyltransferase Activator Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Acute Inflammatory Response Protein Acetylation Negative Regulation Of Cell Proliferation Male Gonad Development Response To Toxic Substance Regulation Of Autophagy Negative Regulation Of Autophagy Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Modification Process Skeletal Muscle Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Negative Regulation Of Glycolytic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Protein-containing Complex Assembly Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Autophagosome Assembly Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Oxidative Phosphorylation Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Female Gonad Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic sclerosis ( 21779181)	Alcohol consumption (drinks per week) ( 30679032) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Crohn's disease ( 28067908) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574) Intelligence (MTAG) ( 29326435) Offspring birth weight ( 31043758) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		8 interacting genes: APP CSNK2B DAPK1 IKBKG MAPK14 NUPR1 PRNP SRPK2	21 interacting genes: ABCG8 ALDH1A1 EP300 FUS KNSTRN MAPRE1 MPHOSPH6 MSL1 NACA NONO NPY5R PAXIP1 PSMD4 PTMA RAN RANBP1 RPL41 SEC11A SET STX18 SYNCRIP
Entrez ID		6171	26471
HPRD ID		17999	17814
Ensembl ID		ENSG00000229117	ENSG00000176046
Uniprot IDs		A0A024RB15 P62945	A0A024QZC4 O60356
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5LKS 5OA3 5VYC 6EK0 6G5H 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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