RPL5 and SPIN1

Number of citations of the paper that reports this interaction (PubMedID 29547122)
4

Data Source:
BioGRID (pull down)

		RPL5	SPIN1
Description		ribosomal protein L5	spindlin 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Protein-containing Complex Synapse Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Spindle Cytosol Nuclear Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome Protein Binding 5S RRNA Binding Ubiquitin Protein Ligase Binding MRNA 5'-UTR Binding Ubiquitin Ligase Inhibitor Activity	Protein Binding Methylated Histone Binding
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Gene Expression Viral Transcription Ribosomal Large Subunit Biogenesis Positive Regulation Of Translation Protein Stabilization Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Neddylation	Chromatin Organization Regulation Of Transcription, DNA-templated Multicellular Organism Development Gamete Generation RRNA Transcription Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Meiotic Cell Cycle
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Diamond-Blackfan anemia (DBA)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Height ( 20881960) Multiple sclerosis ( 19525955 17660530)	Height ( 20881960 31562340 18391951) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		24 interacting genes: CLK1 CSNK2A1 CSNK2B DCC EIF5A HARS1 IPO13 IPO5 IPO7 KPNB1 MAP3K14 MDM2 NVL PDCD4 PPM1D RNA5S7 SPIN1 SPP1 TNIP1 TNPO1 TP73 TSC22D1 UPF2 VHL	4 interacting genes: HSPB1 PRMT6 PTN RPL5
Entrez ID		6125	10927
HPRD ID		04699	18096
Ensembl ID		ENSG00000122406	ENSG00000106723
Uniprot IDs		A2RUM7 P46777	A0A024R297 Q9Y657
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	2NS2 4H75 4MZF 4MZG 4MZH 5JSG 5JSJ 5Y5W 6I8B 6I8L 6I8Y 6QPL
Enriched GO Terms of Interacting Partners?
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