NIF3L1 and CDKN2C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		NIF3L1	CDKN2C
Description		NGG1 interacting factor 3 like 1	cyclin dependent kinase inhibitor 2C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Transcription Factor Binding Identical Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Phosphorylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Oligodendrocyte Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Atrial fibrillation ( 29290336) Height ( 31562340) Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459) Ischemic stroke (large artery atherosclerosis) ( 26732560) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) QRS complex (12-leadsum) ( 27659466) QRS duration ( 27577874 21076409 27659466) Ventricular ectopy ( 29618737) Ventricular ectopy or supraventricular ectopy (pleiotropy) ( 29618737)
Interacting Genes		67 interacting genes: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PNMA1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1	51 interacting genes: AHCYL1 AKT1 ANGPTL4 APLP1 ARNT ATM ATR CCDC90B CCND2 CCNE1 CDK4 CDK6 CDKN2A CDKN2B COPS6 DRAP1 EPHA2 ERBB2 FGFR4 GDF9 GOPC GREB1 GRM1 LATS2 LNX2 LRIF1 LY96 MAP2K3 MAP2K5 MAPK10 MAPK8 MTA3 MYC NAGK NAT2 NF2 NIF3L1 PDGFRA PPP2CA RAF1 RBM48 REL SCGB2A2 SNU13 ST14 STK11 TCF12 TCF4 TLE1 TP53 UNC119
Entrez ID		60491	1031
HPRD ID		10424	04534
Ensembl ID		ENSG00000196290	ENSG00000123080
Uniprot IDs		A0A024R3V5 A0A024R3V7 Q9GZT8	P42773 Q6ICV4
PDB IDs			1BU9 1G3N 1IHB 1MX2 1MX4 1MX6
Enriched GO Terms of Interacting Partners?
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