RDX and SLC9A3R2

Number of citations of the paper that reports this interaction (PubMedID 12499563)
5

Data Source:
HPRD (in vitro)

		RDX	SLC9A3R2
Description		radixin	SLC9A3 regulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Space Plasma Membrane Microvillus Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Stereocilium Cell Tip Extracellular Exosome Cell Periphery	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome
	Molecular Function	RNA Binding Actin Binding Protein Binding Protein Domain Specific Binding Cadherin Binding Protein Kinase A Binding ATPase Binding	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Protein Kinase A Signaling Microvillus Assembly Positive Regulation Of Cell Migration Regulation Of Actin Filament Bundle Assembly Regulation Of Rap Protein Signal Transduction Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of GTPase Activity Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of GTPase Activity Apical Protein Localization Establishment Of Protein Localization Negative Regulation Of Cell Size Barbed-end Actin Filament Capping Establishment Of Endothelial Barrier Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport	Protein-containing Complex Assembly
Pathways		Recycling pathway of L1 Recycling pathway of L1
Drugs		1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Cognitive function ( 24684796) Multiple sclerosis ( 31604244)	Diastolic blood pressure ( 27841878 30578418) Pulse pressure ( 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		19 interacting genes: ABCC2 ARHGDIA CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 KMT2A L1CAM ROCK1 SLC9A3R1 SLC9A3R2 TSC1 VPS11 VWA5A	37 interacting genes: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		5962	9351
HPRD ID		01534	05946
Ensembl ID		ENSG00000137710	ENSG00000065054
Uniprot IDs		B0YJ88 P35241 Q6PKD3	Q15599
PDB IDs			2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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