RABIF and ITGA2

Number of citations of the paper that reports this interaction (PubMedID 10094488)
14

Data Source:
BioGRID (two hybrid)

		RABIF	ITGA2
Description		RAB interacting factor	integrin subunit alpha 2
Image
GO Annotations	Cellular Component	Cytosol Membrane	Nucleus Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Integrin Alpha2-beta1 Complex Axon Terminus Basal Part Of Cell Perinuclear Region Of Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding	Amyloid-beta Binding Virus Receptor Activity Integrin Binding Protein Binding Collagen Binding Collagen Receptor Activity Laminin Binding Heparan Sulfate Proteoglycan Binding Protein-containing Complex Binding Metal Ion Binding Collagen Binding Involved In Cell-matrix Adhesion
	Biological Process	Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Membrane Fusion	Response To Hypoxia Positive Regulation Of Leukocyte Migration Substrate-dependent Cell Migration Hypotonic Response Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Female Pregnancy Blood Coagulation Cell Proliferation Animal Organ Morphogenesis Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Alkaline Phosphatase Activity Response To Amine Response To Muscle Activity Positive Regulation Of Smooth Muscle Cell Migration Extracellular Matrix Organization Mammary Gland Development Positive Regulation Of Cell Projection Organization Cell-substrate Adhesion Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Collagen Binding Response To L-ascorbic Acid Cell Adhesion Mediated By Integrin Collagen-activated Signaling Pathway Response To Drug Positive Regulation Of DNA Binding Skin Morphogenesis Establishment Of Protein Localization Positive Regulation Of Translation Positive Regulation Of Cell Adhesion Positive Regulation Of Smooth Muscle Contraction Viral Entry Into Host Cell Focal Adhesion Assembly Mesodermal Cell Differentiation Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Inflammatory Response Positive Regulation Of Positive Chemotaxis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Phagocytosis, Engulfment Hepatocyte Differentiation Response To Parathyroid Hormone Cellular Response To Mechanical Stimulus Cellular Response To Estradiol Stimulus
Pathways			Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Laminin interactions Syndecan interactions ECM proteoglycans CHL1 interactions Platelet Adhesion to exposed collagen MET activates PTK2 signaling
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Type 2 diabetes ( 30130595)
Interacting Genes		17 interacting genes: ITGA2 ITGA3 ITGA5 ITGA6 KYAT3 LAMTOR5 RAB10 RAB15 RAB1A RAB3A RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544	14 interacting genes: ACTA1 APP AUP1 CD9 COL1A1 COL1A2 COL8A1 FBN2 HSPG2 ITGB1 LAMA1 MMP1 RABIF TSC22D2
Entrez ID		5877	3673
HPRD ID		04566	01893
Ensembl ID		ENSG00000183155	ENSG00000164171
Uniprot IDs		P47224 Q53EV1	P17301
PDB IDs		1FWQ 2FU5	1AOX 1DZI 1PQB 1V7P 4BJ3 5HJ2 5THP 6ND8 6ND9 6NDA 6NDB 6NDC 6NDD 6NDE 6NDF 6NDG 6NDH
Enriched GO Terms of Interacting Partners?
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