RAB2A and MAPKAPK3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RAB2A	MAPKAPK3
Description		RAB2A, member RAS oncogene family	MAPK activated protein kinase 3
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity MAP Kinase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Mitogen-activated Protein Kinase Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Rab Protein Signal Transduction Post-translational Protein Modification	MAPK Cascade Activation Of MAPK Activity Toll-like Receptor Signaling Pathway Signal Transduction Peptidyl-serine Phosphorylation Response To Lipopolysaccharide Response To Cytokine Intracellular Signal Transduction Macropinocytosis Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation	p38MAPK events Oxidative Stress Induced Senescence VEGFA-VEGFR2 Pathway activated TAK1 mediates p38 MAPK activation
Drugs			2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)	Blood protein levels ( 28240269) Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331)
Interacting Genes		19 interacting genes: ASPH BLZF1 CBFB CPA4 FAM114A1 FAM71C GAPDH GDI2 GOLGA2 GORASP2 ICA1 MAPK6 MAPKAPK3 PRKCI RBSN RGS2 RP1 STAMBPL1 TBC1D25	21 interacting genes: APP ATF1 BECN1 CHMP2A COPS6 EEF2 EEF2K EZH2 HSPB1 IGHM MAPK13 MAPK14 NEDD4 NEDD4L RAB2A RCSD1 SMS SRPK2 SUMO3 TCF3 THAP12
Entrez ID		5862	7867
HPRD ID		01539	03678
Ensembl ID		ENSG00000104388	ENSG00000114738
Uniprot IDs		A0A024R7V6 P61019	A0A024R2W7 Q16644
PDB IDs		1Z0A	3FHR 3FXW 3R1N 3SHE
Enriched GO Terms of Interacting Partners?
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