PZP and CPB2

Number of citations of the paper that reports this interaction (PubMedID 8662763)
5

Data Source:
HPRD (in vitro)

		PZP	CPB2
Description		PZP alpha-2-macroglobulin like	carboxypeptidase B2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Extracellular Region Extracellular Space Cell Extracellular Exosome
	Molecular Function	Protease Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity	Metallocarboxypeptidase Activity Zinc Ion Binding
	Biological Process	Female Pregnancy Negative Regulation Of Endopeptidase Activity	Positive Regulation Of Extracellular Matrix Constituent Secretion Proteolysis Blood Coagulation Response To Heat Negative Regulation Of Plasminogen Activation Regulation Of Complement Activation Response To Drug Fibrinolysis Negative Regulation Of Fibrinolysis Cellular Response To Glucose Stimulus Liver Regeneration Negative Regulation Of Hepatocyte Proliferation
Pathways			Metabolism of Angiotensinogen to Angiotensins Regulation of Complement cascade
Drugs			AZD-9684 Prothrombin
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Depression in smokers ( 30219690) Myopia ( 27182965) Non-alcoholic fatty liver disease histology (AST) ( 20708005) Obesity-related traits ( 23251661) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Blood protein levels ( 30072576 29875488 28240269) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355)
Interacting Genes		6 interacting genes: CPB2 KLK3 MMP2 MMP9 TGFB1 TGFB2	6 interacting genes: A2M C5 F2 PLG PZP TINAG
Entrez ID		5858	1361
HPRD ID		07178	04374
Ensembl ID		ENSG00000126838	ENSG00000080618
Uniprot IDs			A0A087WSY5 Q96IY4
PDB IDs			3D66 3D67 3D68 3LMS 4P10 5HVF 5HVG 5HVH
Enriched GO Terms of Interacting Partners?
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