RHOU and ID2

Number of citations of the paper that reports this interaction (PubMedID 26598620)
20

Data Source:
BioGRID (pull down)

		RHOU	ID2
Description		ras homolog family member U	inhibitor of DNA binding 2
Image
GO Annotations	Cellular Component	Golgi Membrane Podosome Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Ion Channel Binding Protein Dimerization Activity Transcription Regulator Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Endocytosis Cytoskeleton Organization Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Rac Protein Signal Transduction Cytokine-mediated Signaling Pathway Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cdc42 Protein Signal Transduction Regulation Of Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Targeting To Mitochondrion	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Natural Killer Cell Differentiation Thigmotaxis Membranous Septum Morphogenesis Bundle Of His Development Multicellular Organism Development Adult Locomotory Behavior Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Regulation Of Lipid Metabolic Process Olfactory Bulb Development Cell Differentiation Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Enucleate Erythrocyte Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Locomotor Rhythm Negative Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Macrophage Differentiation Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cell Maturation Peyer's Patch Development Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Adipose Tissue Development Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Cellular Response To Lithium Ion Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Negative Regulation Of Core Promoter Binding Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Neural Precursor Cell Proliferation
Pathways		Rho GTPase cycle Interleukin-4 and Interleukin-13 signaling	NGF-stimulated transcription
Drugs
Diseases
GWAS		Aging ( 22773346) Basal cell carcinoma ( 24403052 25855136 27539887 18849993) Chronic lymphocytic leukemia ( 28165464) Dental caries ( 23259602) Endometriosis ( 20844546) Mercury levels ( 26025379) Non-melanoma skin cancer ( 29739929) Response to antidepressants in depression ( 27622933) Type 2 diabetes ( 23300278)	Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 27182965) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Cognitive decline rate in late mild cognitive impairment ( 26252872) IgE levels ( 22075330) Itch intensity from mosquito bite ( 28199695) Mean corpuscular volume ( 28017375) PR interval ( 29127183 30046033 31217584) Self-reported allergy ( 23817569)
Interacting Genes		128 interacting genes: ACAD8 ADM2 ALG13 ANGPT4 ANXA4 ANXA6 AP1S1 ARHGEF25 ARNTL AS3MT ATP5MG ATP6AP1 BDNF BNIPL BRF1 BRINP3 C14orf119 CDKL4 CFAP100 CHRNA4 CLEC7A CPNE3 CTCF CUL5 DACT2 DMRT2 DNM2 DOK4 DSCR8 EIF4B ELP5 EMC2 ERF ERO1A ESYT1 FAM110B FCHO2 FKBP15 GALNTL5 GLI3 GPRIN2 GRB2 H2BC14 HCAR1 HINT3 HSD17B13 ID2 IFFO1 IL17F INSM2 JAM3 KAAG1 KIAA1191 KLRC3 LANCL2 LARS2 LAYN LMO7 LYL1 MARCKS ME3 MOS MRAS MRPL15 NCK1 NCR1 NPM3 NR1H2 NRBF2 NXPH4 OXCT2 P4HTM PAK1 PAK4 PCDHGA4 PDLIM3 PGK1 PIP5K1A PLCG1 PLEK PLOD3 POT1 PRB1 PRPF18 PSMA4 PXN QTRT1 RAB40A RAD51D RALBP1 RASSF1 RBIS RPL23AP5 RPS15A RPS17P16 S100A4 SEC14L4 SEMA3G SEPTIN6 SIVA1 SKIV2L SLC26A1 SNU13 SOX4 SSC4D STX16 SYK TCN2 TEKT2 TMEM106A TMEM169 TMEM255B TRIM59 USP37 UTP3 VWA5A WNT6 XPA ZFAND2B ZFP64 ZKSCAN7 ZNF117 ZNF177 ZNF20 ZNF569 ZNF625 ZNF747 ZNF84	44 interacting genes: ADD1 ASB4 CDK2 DYRK1A DYRK1B ELK1 ELK3 ELK4 ELOC GATA4 HES1 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 NR0B2 PAX2 PAX5 PAX8 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 RHOU RIN3 SREBF1 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TNS2 TSTA3 UNC119
Entrez ID		58480	3398
HPRD ID		06965	02664
Ensembl ID		ENSG00000116574	ENSG00000115738
Uniprot IDs		A0A024R3Q7 Q7L0Q8	Q02363 Q53T66
PDB IDs		2Q3H	4AYA
Enriched GO Terms of Interacting Partners?
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