PURA and ADAP1

Number of citations of the paper that reports this interaction (PubMedID 12565890)
4

Data Source:
HPRD (in vitro)

		PURA	ADAP1
Description		purine rich element binding protein A	ArfGAP with dual PH domains 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus DNA Replication Factor A Complex Dendrite Cytoplasm Neuronal Cell Body Postsynapse Glutamatergic Synapse	Nucleus Cytoplasm Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding Double-stranded Telomeric DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding Transcription Factor Binding Purine-rich Negative Regulatory Element Binding Sequence-specific DNA Binding SMAD Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Unwinding Involved In DNA Replication DNA Replication Initiation Nervous System Development Positive Regulation Of Cell Proliferation Negative Regulation Of Translation Cell Differentiation Lymphocyte Proliferation Epithelial Cell Proliferation Dendritic Transport Of Messenger Ribonucleoprotein Complex	Cell Surface Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of GTPase Activity
Pathways			Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		10 interacting genes: ADAP1 CCNT1 CDK5 E2F1 IL7R PURB RAF1 RB1 SP1 YBX1	23 interacting genes: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1
Entrez ID		5813	11033
HPRD ID		02721	09733
Ensembl ID		ENSG00000185129	ENSG00000105963
Uniprot IDs		Q00577	A8K3A2 B4DUZ7 O75689
PDB IDs			3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?
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