MIER1 and TMEM171

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MIER1	TMEM171
Description		MIER1 transcriptional regulator	transmembrane protein 171
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Transcriptional Repressor Complex Protein-containing Complex	Integral Component Of Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Repressing Transcription Factor Binding DNA Binding Transcription Corepressor Activity Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Positive Regulation Of Chromatin Silencing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lymphocyte percentage of white cells ( 27863252) Ulcerative colitis ( 28067908)	Aspartate aminotransferase levels ( 29403010) Blood urea nitrogen levels ( 29403010) Creatinine levels ( 29124443) Eyebrow thickness ( 26926045) Factor VIII levels ( 30586737) Hyperuricemia ( 29124443) Monobrow thickness ( 26926045) Renal function-related traits (BUN) ( 22797727) Serum uric acid levels ( 29124443) Urate levels ( 31578528 23263486) Urea levels ( 31015462) vWF levels ( 30586737)
Interacting Genes		6 interacting genes: APP CREBBP H3-4 HDAC1 SP1 TMEM171	1 interacting genes: MIER1
Entrez ID		57708	134285
HPRD ID		11362	14057
Ensembl ID		ENSG00000198160	ENSG00000157111
Uniprot IDs		Q8N108	Q8WVE6
PDB IDs
Enriched GO Terms of Interacting Partners?
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