TAOK1 and C8orf33

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TAOK1	C8orf33
Description		TAO kinase 1	chromosome 8 open reading frame 33
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Microtubule Cytoskeleton Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Alpha-tubulin Binding Protein Serine/threonine Kinase Activator Activity Tau Protein Binding Beta-tubulin Binding Tau-protein Kinase Activity	Protein Binding
	Biological Process	Activation Of MAPKK Activity Activation Of MAPK Activity Microtubule Cytoskeleton Organization DNA Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Negative Regulation Of Microtubule Depolymerization Mitotic G2 DNA Damage Checkpoint Activation Of JUN Kinase Activity Regulation Of Mitotic Cell Cycle Phosphorylation Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade G2 DNA Damage Checkpoint Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Positive Regulation Of JNK Cascade Protein Autophosphorylation Regulation Of Cytoskeleton Organization Neuron Cellular Homeostasis Regulation Of Microtubule Cytoskeleton Organization Execution Phase Of Apoptosis Positive Regulation Of Protein Acetylation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419 24026423 19110211 19820697 22423221 27863252) Platelet count ( 22139419 29066854)
Interacting Genes		7 interacting genes: C8orf33 CSNK1E DYNC1I1 GEMIN7 MAP2K3 MARK1 WT1	42 interacting genes: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CRELD2 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MAPK8IP2 MDFI MRFAP1 NGEF NOL7 PI4KA PNMA1 RASSF1 SF3B2 TAOK1 TRIM23 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331
Entrez ID		57551	65265
HPRD ID		15467	07951
Ensembl ID		ENSG00000160551	ENSG00000182307
Uniprot IDs		A0A024QZ70 Q7L7X3	Q9H7E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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