ADGRB1 and PDZD2

Number of citations of the paper that reports this interaction (PubMedID 23782696)
30

Data Source:
BioGRID (unspecified method)

		ADGRB1	PDZD2
Description		adhesion G protein-coupled receptor B1	PDZ domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Postsynaptic Density Integral Component Of Membrane Dendrite Dendritic Spine Perinuclear Region Of Cytoplasm	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Cell-cell Junction
	Molecular Function	Lipopolysaccharide Binding Phosphatidylserine Binding G Protein-coupled Receptor Activity Protein Binding PDZ Domain Binding
	Biological Process	Phagocytosis, Recognition Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Peripheral Nervous System Development Muscle Organ Development Negative Regulation Of Cell Proliferation Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Catabolic Process Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Innate Immune Response Regulation Of Synaptic Plasticity Defense Response To Gram-negative Bacterium Positive Regulation Of Synapse Assembly Positive Regulation Of Myoblast Fusion Positive Regulation Of Reactive Oxygen Species Biosynthetic Process	Cell Adhesion
Pathways
Drugs
Diseases
GWAS			Cerebrospinal fluid t-tau levels in Alzheimer's disease dementia ( 29274321) Chronic obstructive pulmonary disease ( 29394082) Corpus callosum central volume ( 31530798) Height ( 28552196) Intracranial aneurysm ( 29531279) Myocardial infarction ( 26708285) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Renal cell carcinoma ( 23184150) Response to serotonin reuptake inhibitors in major depressive disorder (plasma drug and metabolite levels) ( 24528284) Self-reported childhood asthma in adult smokers ( 30373671) Vertical cup-disc ratio ( 31798171 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Working memory ( 31598132)
Interacting Genes		18 interacting genes: BAIAP2 BAIAP3 DLG1 DLG4 ELMO1 ERBB2 LIN7A LRRC7 MAGI1 MAGI2 MAGI3 PATJ PDZD2 PHYHIP SNTA1 SNTB1 SNTB2 SNTG2	5 interacting genes: ADGRB1 CST3 CTNND2 NRXN1 PKP4
Entrez ID		575	23037
HPRD ID		04062	10142
Ensembl ID		ENSG00000181790	ENSG00000133401
Uniprot IDs		O14514	A0A024RE15 O15018
PDB IDs
Enriched GO Terms of Interacting Partners?
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