PTGDS and PTGER1

Number of citations of the paper that reports this interaction (PubMedID 8253813)
48

Data Source:
HPRD (in vivo)

		PTGDS	PTGER1
Description		prostaglandin D2 synthase	prostaglandin E receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Cell Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Prostaglandin-D Synthase Activity Retinoid Binding Fatty Acid Binding Protein Binding	Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding
	Biological Process	Prostaglandin Biosynthetic Process Cyclooxygenase Pathway Regulation Of Circadian Sleep/wake Cycle, Sleep	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Lipopolysaccharide Negative Regulation Of Gastric Emptying
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Prostanoid ligand receptors G alpha (q) signalling events
Drugs			Bupivacaine Carboprost Tromethamine Alprostadil Bimatoprost Dinoprostone Iloprost Limaprost
Diseases
GWAS		Beta-trace protein levels ( 23328707) Blood protein levels ( 30072576 29875488) Corneal structure ( 23291589)
Interacting Genes		17 interacting genes: AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 MLH1 PTGER1 PTGER2 PTGFR SHBG	5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR
Entrez ID		5730	5731
HPRD ID		08904	08903
Ensembl ID		ENSG00000107317	ENSG00000160951
Uniprot IDs		A0A024R8G3 P41222	P34995
PDB IDs		2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9
Enriched GO Terms of Interacting Partners?
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