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BAD and S100A10
Number of citations of the paper that reports this interaction (PubMedID
9369453
)
44
Data Source:
BioGRID
(two hybrid, pull down)
HPRD
(two hybrid, in vivo)
BAD
S100A10
Description
BCL2 associated agonist of cell death
S100 calcium binding protein A10
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Extracellular Region
Endoplasmic Reticulum
Extrinsic Component Of Plasma Membrane
Membrane Raft
Collagen-containing Extracellular Matrix
Extracellular Exosome
AnxA2-p11 Complex
Molecular Function
Protein Binding
Phospholipid Binding
Lipid Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Protein Kinase Binding
Protein Phosphatase Binding
Protein Phosphatase 2B Binding
Protein Kinase B Binding
14-3-3 Protein Binding
Calcium Ion Binding
Protein Binding
Lipid Binding
Protein Homodimerization Activity
Ion Channel Binding
Biological Process
Release Of Cytochrome C From Mitochondria
Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Glucose Catabolic Process
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Spermatogenesis
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Response To Glucose
Positive Regulation Of Autophagy
Positive Regulation Of Mitochondrial Membrane Potential
Suppression By Virus Of Host Apoptotic Process
Cytokine-mediated Signaling Pathway
Cerebral Cortex Development
Positive Regulation Of Insulin Secretion
Response To Estradiol
Response To Progesterone
Positive Regulation Of Glucokinase Activity
Response To Testosterone
Response To Oleic Acid
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Response To Hydrogen Peroxide
Glucose Homeostasis
Positive Regulation Of Apoptotic Process
Response To Amino Acid
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Type B Pancreatic Cell Proliferation
Response To Ethanol
Positive Regulation Of B Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Proteolysis
ADP Metabolic Process
ATP Metabolic Process
Regulation Of Mitochondrial Membrane Permeability
Pore Complex Assembly
Positive Regulation Of Epithelial Cell Proliferation
Response To Glucocorticoid
Response To Calcium Ion
Positive Regulation Of Apoptotic Process By Virus
Cellular Response To Chromate
Cellular Response To Mechanical Stimulus
Cellular Response To Nicotine
Cellular Response To Lipid
Cellular Response To Hypoxia
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Extrinsic Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Intrinsic Apoptotic Signaling Pathway
Activation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Neuron Death
Response To Benzene
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress
Positive Regulation Of Granulosa Cell Apoptotic Process
Positive Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Membrane Raft Assembly
Vesicle Budding From Membrane
Response To Drug
Positive Regulation Of GTPase Activity
Positive Regulation Of Binding
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Focal Adhesion Assembly
Protein Localization To Plasma Membrane
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways
Activation of BAD and translocation to mitochondria
Activation of BAD and translocation to mitochondria
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
NRAGE signals death through JNK
AKT phosphorylates targets in the cytosol
Constitutive Signaling by AKT1 E17K in Cancer
Dissolution of Fibrin Clot
Drugs
Navitoclax
Phenethyl Isothiocyanate
Diseases
GWAS
Crohn's disease (
28067908
)
Heel bone mineral density (
30598549
)
Platelet count (
22423221
)
Sarcoidosis (
22837380
)
Vitiligo (
27723757
)
Asthma (
31619474
)
Diverticular disease (
30177863
)
Urinary metabolite levels in chronic kidney disease (
29545352
)
Urinary metabolite ratios in chronic kidney disease (
29545352
)
Interacting Genes
43 interacting genes:
AKT1
ARAF
BCL2
BCL2A1
BCL2L1
BCL2L10
BCL2L2
BRAF
CDKN1A
CREB3L3
EWSR1
HRK
KEAP1
MAP2K5
MAPK8
MCL1
PAK1
PAK5
PIM1
PIM2
PIM3
PPP1CA
PPP3CA
PRDX2
PRKACA
PRKCI
RAF1
RPS6KA1
RPS6KA2
RPS6KA3
RPS6KA5
S100A10
SFN
SNCA
STEAP3
SUMO2
WASF1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
13 interacting genes:
ANXA2
ANXA7
BAD
CDK16
COPS6
CTSB
FSHR
KCNK3
PLA2G4C
PLG
SETDB1
TRPV5
TRPV6
Entrez ID
572
6281
HPRD ID
04409
00232
Ensembl ID
ENSG00000002330
ENSG00000197747
Uniprot IDs
A0A024R562
Q92934
P60903
PDB IDs
1G5J
1A4P
1BT6
4DRW
4FTG
4HRE
4HRG
4HRH
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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