TWSG1 and CHRD

Number of citations of the paper that reports this interaction (PubMedID 11260715)
50

Data Source:
HPRD (in vitro)

		TWSG1	CHRD
Description		twisted gastrulation BMP signaling modulator 1	chordin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Transforming Growth Factor Beta Binding	Protein Binding Heparin Binding Cytokine Binding Syndecan Binding
	Biological Process	Ossification Mesoderm Formation Negative Regulation Of Cytokine Production Transforming Growth Factor Beta Receptor Signaling Pathway Salivary Gland Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Hemopoiesis Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation	Skeletal System Development Osteoblast Differentiation Gastrulation With Mouth Forming Second Mesoderm Formation Positive Regulation Of Mesenchymal Cell Proliferation BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Negative Regulation Of Cell Migration Negative Regulation Of BMP Signaling Pathway Forebrain Development Floor Plate Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23064961)	Diisocyanate-induced asthma ( 25918132) Platelet count ( 20139978) Plateletcrit ( 27863252)
Interacting Genes		5 interacting genes: BMP1 BMP4 CHRD SGTA TNS2	26 interacting genes: ATN1 BMP1 BMP2 CATSPER1 CD36 F2R HOXA1 HRG KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 KRTAP9-2 MEOX2 NOTCH2NLA NR0B2 OTX1 PLSCR1 SMAD3 SPRY2 TLL1 TWSG1
Entrez ID		57045	8646
HPRD ID		05443	04592
Ensembl ID		ENSG00000128791	ENSG00000090539
Uniprot IDs		Q9GZX9	E7ESX1 Q8N2W7 Q9H2X0
PDB IDs
Enriched GO Terms of Interacting Partners?
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