DIABLO and UFM1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		DIABLO	UFM1
Description		diablo IAP-binding mitochondrial protein	ubiquitin fold modifier 1
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex	Nucleus Cytoplasm Endoplasmic Reticulum
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Apoptotic Process Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway	Brain Development Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Protein Ufmylation Protein K69-linked Ufmylation
Pathways		Release of apoptotic factors from the mitochondria SMAC (DIABLO) binds to IAPs SMAC (DIABLO) binds to IAPs SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC, XIAP-regulated apoptotic response Regulation of the apoptosome activity
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS			Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Low vWF levels ( 26486471) Schizophrenia ( 30285260)
Interacting Genes		23 interacting genes: AGTRAP AREL1 ARL6IP1 ARNT BEX3 BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 CASP9 E2F1 EEF1A1 HTRA2 LTBR MAML2 NR4A1 SBNO1 SLC25A47 UBE2K UFM1 XIAP ZNF746	14 interacting genes: ARHGDIA ARHGDIB DIABLO GSK3B RPS6KA6 TSC22D2 UBA5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W
Entrez ID		56616	51569
HPRD ID		05560	15644
Ensembl ID		ENSG00000184047	ENSG00000120686
Uniprot IDs		A0A024RBT2 A0A0S2Z5P6 A0A0S2Z5U7 K7X1S0 Q502X2 Q9NR28	P61960
PDB IDs		1FEW 1G3F 1G73 1OXQ 1TW6 1XB0 1XB1 3D9U 3UIH 3UIJ 4TX5	1WXS 5HKH 5IA7 5IA8 5IAA 5L95 6H77
Enriched GO Terms of Interacting Partners?
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