PRMT8 and TAF15

Number of citations of the paper that reports this interaction (PubMedID 16051612)
76

Data Source:
BioGRID (enzymatic study)

		PRMT8	TAF15
Description		protein arginine methyltransferase 8	TATA-box binding protein associated factor 15
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GO Annotations	Cellular Component	Nucleus Plasma Membrane Anchored Component Of The Cytoplasmic Side Of The Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Enzyme Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Identical Protein Binding Protein Homodimerization Activity S-adenosyl-L-methionine Binding	DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Methylation Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Arginine Methylation Regulation Of Protein Binding Protein Homooligomerization	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter RNA Splicing Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS		Cardiac Troponin-T levels ( 31014085) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) HDL cholesterol ( 19060911)	Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		13 interacting genes: CEP162 COIL DCAF8 ERC1 GPATCH2L H4C1 OFCC1 PPARA PRMT1 SERBP1 TAF15 VHL ZNF451	22 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 POLR2C POLR2E POLR2G PRMT8 SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		56341	8148
HPRD ID		11029	09031
Ensembl ID		ENSG00000111218	ENSG00000270647
Uniprot IDs		Q59GT2 Q9NR22	Q92804
PDB IDs		4X41 5DST	2MMY
Enriched GO Terms of Interacting Partners?
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