MAPK13 and EEF2K

Number of citations of the paper that reports this interaction (PubMedID 11500363)
81

Data Source:
HPRD (in vitro, in vivo)

		MAPK13	EEF2K
Description		mitogen-activated protein kinase 13	eukaryotic elongation factor 2 kinase
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Cytosol Postsynaptic Density Dendritic Spine
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding	Protein Kinase Activity Elongation Factor-2 Kinase Activity Calcium Ion Binding Calmodulin Binding ATP Binding Translation Factor Activity, RNA Binding
	Biological Process	Response To Osmotic Stress Cell Cycle Regulation Of Gene Expression Peptidyl-serine Phosphorylation Positive Regulation Of Interleukin-6 Production Cellular Response To UV Intracellular Signal Transduction Positive Regulation Of Inflammatory Response Stress-activated MAPK Cascade Cellular Response To Hydrogen Peroxide Cellular Response To Interleukin-1 Cellular Response To Sorbitol Cellular Response To Anisomycin Cellular Response To Sodium Arsenite	Response To Ischemia Translational Elongation Regulation Of Protein Autophosphorylation Cellular Response To Insulin Stimulus Negative Regulation Of Apoptotic Process Positive Regulation Of Endocytosis Protein Autophosphorylation Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis Cellular Response To Calcium Ion Cellular Response To CAMP Cellular Response To Anoxia Cellular Response To Brain-derived Neurotrophic Factor Stimulus Response To Prolactin
Pathways		NOD1/2 Signaling Pathway p38MAPK events DSCAM interactions VEGFA-VEGFR2 Pathway	mTORC1-mediated signalling
Drugs		KC706
Diseases
GWAS		Birth weight ( 31043758) Blood protein levels ( 30072576 29875488) Offspring birth weight ( 31043758)	Heel bone mineral density ( 30598549)
Interacting Genes		16 interacting genes: AKIP1 ANKLE2 APP ATF2 EEF2K FGF12 GPX4 HTRA2 MAP2K6 MAP3K4 MAPKAPK3 MAPKAPK5 MAPT MBP SMAD4 SQSTM1	17 interacting genes: CDK1 EEF2 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 MAPKAPK2 MAPKAPK3 MAPKAPK5 PRKAA1 PRKAA2 PRKACA RPS6KA1 RPS6KB1 RPS6KB2
Entrez ID		5603	29904
HPRD ID		09113	07369
Ensembl ID		ENSG00000156711	ENSG00000103319
Uniprot IDs		A0A024RD04 O15264	O00418
PDB IDs		3COI 4EYJ 4EYM 4MYG 4YNO 5EKN 5EKO	5J8H 5KS5 6NX4
Enriched GO Terms of Interacting Partners?
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