GSDMB and HIVEP1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GSDMB	HIVEP1
Description		gasdermin B	HIVEP zinc finger 1
Image
GO Annotations	Cellular Component	Cellular_component Cytosol Plasma Membrane	Nucleus Nucleoplasm Mitochondrion Nuclear Body
	Molecular Function	Phosphatidylserine Binding Molecular_function Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Biological_process Defense Response To Bacterium Pyroptosis	Negative Regulation Of Transcription By RNA Polymerase II BMP Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Adult asthma ( 30787307) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 21804549 31361310 30929738 20860503 31619474 29273806 28461288) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738 27611488 24241537 29273806) Asthma (time to onset) ( 27130862) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Atrial fibrillation ( 30061737) Bronchial hyperresponsiveness in asthma ( 27439200) Cervical cancer ( 23817570) Crohn's disease ( 28067908) Dermatomyositis or juvenile dermatomyositis ( 26362759) Feeling miserable ( 29500382) Fractional exhaled nitric oxide (childhood) ( 24315451) IgM levels ( 28628107) Inflammatory bowel disease ( 28067908 23128233) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Monocyte percentage of white cells ( 27863252) Primary biliary cholangitis ( 23000144 20639880 30643196) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Self-reported allergy ( 23817569) Subcutaneous adipose tissue ( 27918534) Systemic lupus erythematosus ( 26502338) Systemic sclerosis ( 28314753 31672989) Type 1 diabetes ( 25751624) Ulcerative colitis ( 28067908) White blood cell count ( 21738480)	Alcohol and nicotine co-dependence ( 22488850) Body mass index ( 28892062 25673413 29273807) Chronotype ( 30696823) Feeling worry ( 29500382) Figural/spatial cognitive ability ( 31620175) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Metabolite levels ( 23823483) Takayasu arteritis ( 25604533)
Interacting Genes		8 interacting genes: AGT APP CLK1 HIVEP1 IGFBP2 ORM1 PEBP1 SERPINA1	37 interacting genes: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A CLK1 DNAJA1 EMG1 GAA GSDMB HPD HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A RIDA SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 SRPK2 STAT3 TMEM176A
Entrez ID		55876	3096
HPRD ID		17082	01925
Ensembl ID		ENSG00000073605	ENSG00000095951
Uniprot IDs		Q8TAX9	P15822
PDB IDs		5TIB 5TJ2 5TJ4	1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?
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