TMEM126B and ALG8

		TMEM126B	ALG8
Description		transmembrane protein 126B	ALG8 alpha-1,3-glucosyltransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	Alpha-1,3-mannosyltransferase Activity Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Protein Binding Dolichyl Pyrophosphate Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity
	Biological Process	Biological_process Mitochondrial Respiratory Chain Complex I Assembly	Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide-lipid Intermediate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Mannosylation
Pathways		Complex I biogenesis	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG8 causes ALG8-CDG (CDG-1h)
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Height ( 19570815) Metabolite levels ( 23823483)	Depression in smokers ( 30219690) Tourette syndrome ( 30818990)
Interacting Genes		4 interacting genes: ALG8 APP MRFAP1L1 NARS2	8 interacting genes: CREB3 IQGAP2 LMNA NAE1 NARS2 RPS6KA5 RSF1 TMEM126B
Entrez ID		55863	79053
HPRD ID		13715	10480
Ensembl ID		ENSG00000171204	ENSG00000159063
Uniprot IDs		A0A024R5L4 Q8IUX1	A0A024R5K5 Q9BVK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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