VPS11 and UVRAG

Number of citations of the paper that reports this interaction (PubMedID 18552835)
281

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS11	UVRAG
Description		VPS11 core subunit of CORVET and HOPS complexes	UV radiation resistance associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane	Lytic Vacuole Autophagosome Membrane Chromosome, Centromeric Region Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endoplasmic Reticulum Centrosome Midbody Phagocytic Vesicle DNA-dependent Protein Kinase Complex
	Molecular Function	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding	SNARE Binding Protein Binding SH3 Domain Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Regulation Of Protein Stability Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport	DNA Repair Retrograde Vesicle-mediated Transport, Golgi To ER Autophagy Spindle Organization Chromosome Segregation Centrosome Cycle Regulation Of Cytokinesis Receptor Catabolic Process SNARE Complex Assembly Viral Entry Into Host Cell Maintenance Of Golgi Location Regulation Of Protein Serine/threonine Kinase Activity Multivesicular Body Sorting Pathway Autophagosome Maturation Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Autophagosome Maturation
Pathways			Macroautophagy
Drugs
Diseases
GWAS		Body mass index ( 29273807) Coronary artery disease ( 29212778)	Asthma ( 31619474) HDL cholesterol ( 30275531) Hemoglobin concentration ( 27863252)
Interacting Genes		37 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45 WNT1	8 interacting genes: CSNK1A1 MTOR OS9 VPS11 VPS16 VPS18 VPS33B ZRANB1
Entrez ID		55823	7405
HPRD ID		12258	03929
Ensembl ID		ENSG00000160695	ENSG00000198382
Uniprot IDs		A0A087WXL6 B7Z879 Q9H270	Q9P2Y5
PDB IDs
Enriched GO Terms of Interacting Partners?
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