VPS35 and VPS29

Number of citations of the paper that reports this interaction (PubMedID 11102511)
98

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid)

		VPS35	VPS29
Description		VPS35 retromer complex component	VPS29 retromer complex component
Image
GO Annotations	Cellular Component	Mitochondrion Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Postsynaptic Density Retromer Complex Retromer, Cargo-selective Complex Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome Tubular Endosome Presynapse Glutamatergic Synapse Mitochondrion-derived Vesicle	Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Retromer Complex Retromer, Cargo-selective Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding D1 Dopamine Receptor Binding	Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Lysosome Organization Synapse Assembly Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Mitochondrion Organization Viral Process Wnt Signaling Pathway Regulation Of Macroautophagy Regulation Of Protein Stability Protein Destabilization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Homooligomerization Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Mitochondrial Fragmentation Involved In Apoptotic Process Transcytosis Negative Regulation Of Inflammatory Response Voluntary Musculoskeletal Movement Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Death Positive Regulation Of Wnt Protein Secretion Positive Regulation Of Mitochondrial Fission Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Locomotion Involved In Locomotory Behavior Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Mitochondrion To Lysosome Transport Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Negative Regulation Of Neuron Death Negative Regulation Of Late Endosome To Lysosome Transport Regulation Of Dendritic Spine Maintenance Positive Regulation Of Dopamine Biosynthetic Process Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cellular Protein Localization Negative Regulation Of Lysosomal Protein Catabolic Process Regulation Of Presynapse Assembly Retrograde Transport, Endosome To Plasma Membrane Regulation Of Terminal Button Organization	Intracellular Protein Transport Regulation Of Autophagy Viral Process Wnt Signaling Pathway Endocytic Recycling Retrograde Transport, Endosome To Golgi Retrograde Transport, Endosome To Plasma Membrane
Pathways		WNT ligand biogenesis and trafficking	WNT ligand biogenesis and trafficking
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: APP MTNR1B SLC11A2 SNX1 SNX3 VEGFA VPS26B VPS29 ZNF512B	5 interacting genes: APP FRA10AC1 RAB7A RGS2 VPS35
Entrez ID		55737	51699
HPRD ID		06085	09499
Ensembl ID		ENSG00000069329	ENSG00000111237
Uniprot IDs		Q96QK1	A0A384MR19 F8VXU5 Q9UBQ0
PDB IDs		2R17 5F0J 5F0K 5F0L 5F0M 5F0P 5OSH 5OSI	1W24 2R17 5GTU 5OSH 5OSI 5WYH
Enriched GO Terms of Interacting Partners?
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