DOK4 and STAT2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		DOK4	STAT2
Description		docking protein 4	signal transducer and activator of transcription 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Axon Guidance	Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Defense Response JAK-STAT Cascade Viral Process Cytokine-mediated Signaling Pathway Regulation Of Cell Proliferation Response To Peptide Hormone Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Mitochondrial Fission
Pathways		RET signaling	Interleukin-20 family signaling Interferon alpha/beta signaling Regulation of IFNA signaling Regulation of IFNA signaling
Drugs
Diseases
GWAS			Axial length ( 24144296) Height ( 20881960 25429064 23456168) Inflammatory skin disease ( 25574825) Macular thickness ( 30535121) Psoriasis ( 25903422 25574825 23143594 19169254) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624)
Interacting Genes		18 interacting genes: CRK EGFR ERBB2 FYN IGF1R INSR LIX1 MAPRE3 OLIG1 OPRM1 PTK2 RASA1 RBP7 RET RHOU SRC STAT2 TEK	20 interacting genes: AURKA CREBBP CXCR4 DOK4 EGFR EP300 FNTA GAA HDAC1 IFNAR1 IFNAR2 IRF9 IWS1 JAK1 JAK2 MED14 SMARCA4 STAT1 STAT6 TYK2
Entrez ID		55715	6773
HPRD ID		16316	02778
Ensembl ID		ENSG00000125170	ENSG00000170581
Uniprot IDs		A0A024R6S2 H3BQ19 Q8TEW6	P52630 R9QE65
PDB IDs			2KA4
Enriched GO Terms of Interacting Partners?
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