DOCK10 and RHOJ

Number of citations of the paper that reports this interaction (PubMedID 15710388)
17

Data Source:
HPRD (in vitro)

		DOCK10	RHOJ
Description		dedicator of cytokinesis 10	ras homolog family member J
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cell Junction Dendritic Spine Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Molecular_function Guanyl-nucleotide Exchange Factor Activity	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	B Cell Homeostasis Marginal Zone B Cell Differentiation Small GTPase Mediated Signal Transduction Regulation Of Cell Migration Positive Regulation Of GTPase Activity Dendritic Spine Morphogenesis	Angiogenesis Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Retina Vasculature Morphogenesis In Camera-type Eye Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways		Factors involved in megakaryocyte development and platelet production	Rho GTPase cycle
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) IgE levels in asthmatics (D.p. specific) ( 23967269) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244) Platelet distribution width ( 27863252) Response to bupropion and depression ( 27622933) Response to exercise (triglyceride level interaction) ( 26491034) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)	Endometriosis ( 28881265) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: LURAP1 MAGEA11 RHOJ	20 interacting genes: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 CDC42EP1 DOCK10 DOCK8 MEOX2 PAK1 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS WASL
Entrez ID		55619	57381
HPRD ID		10919	09632
Ensembl ID		ENSG00000135905	ENSG00000126785
Uniprot IDs		Q96BY6	A0A024R692 Q7Z513 Q9H4E5
PDB IDs
Enriched GO Terms of Interacting Partners?
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