QRSL1 and KRT8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		QRSL1	KRT8
Description		glutaminyl-tRNA amidotransferase subunit QRSL1	keratin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Glutamyl-tRNA(Gln) Amidotransferase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Amidase Activity Protein Binding ATP Binding Glutaminyl-tRNA Synthase (glutamine-hydrolyzing) Activity	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding
	Biological Process	Regulation Of Protein Stability Mitochondrial Translation Glutaminyl-tRNAGln Biosynthesis Via Transamidation	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways			Keratinization Formation of the cornified envelope
Drugs			Tenecteplase Copper
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)	Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 21743057)
Interacting Genes		2 interacting genes: KRT8 XRCC6	35 interacting genes: ANXA1 BYSL CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 TCHP TFIP11 TROAP WBP2
Entrez ID		55278	3856
HPRD ID		15199	01015
Ensembl ID		ENSG00000130348	ENSG00000170421
Uniprot IDs		Q9H0R6	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?
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