SMU1 and LSM4

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		SMU1	LSM4
Description		SMU1 DNA replication regulator and spliceosomal factor	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
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GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	P-body Nucleus Nucleoplasm U6 SnRNP Cytosol Membrane Protein-containing Complex Neuron Projection U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding PH Domain Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Splicing Viral Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Cytoplasmic MRNA Processing Body Assembly Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Chronotype ( 30696823) Estimated glomerular filtration rate ( 30604766) Gastroesophageal reflux disease ( 31527586) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		6 interacting genes: CD2BP2 H2BC21 LSM4 LSM8 MRFAP1L1 YBX1	19 interacting genes: CALCOCO2 COX5B IKZF1 L3MBTL3 LSM1 LSM7 NMI PLEKHA5 PSTPIP1 RHOXF2 SLC22A2 SMIM14 SMN1 SMU1 SNRPE TOE1 TOP1 XRN1 ZBTB10
Entrez ID		55234	25804
HPRD ID		11588	06284
Ensembl ID		ENSG00000122692	ENSG00000130520
Uniprot IDs		A0MNN4 Q2TAY7	Q9Y4Z0 U3KQK1
PDB IDs		5O9Z 6AHD 6Q8F 6Q8I 6Q8J	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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