SMG8 and SMG1

Number of citations of the paper that reports this interaction (PubMedID 19417104)
89

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology)

		SMG8	SMG1
Description		SMG8 nonsense mediated mRNA decay factor	SMG1 nonsense mediated mRNA decay associated PI3K related kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Telomeric DNA Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Protein Kinase Activity	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay DNA Repair MRNA Export From Nucleus Peptidyl-serine Phosphorylation Regulation Of Telomere Maintenance Protein Autophosphorylation Phosphatidylinositol Phosphorylation Regulation Of Response To DNA Damage Stimulus
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Health literacy ( 31250787) Heel bone mineral density ( 30598549)
Interacting Genes		2 interacting genes: PDZD11 SMG1	9 interacting genes: CDH5 ELOB PRKCI SMAD9 SMG5 SMG8 UPF1 UPF2 UPF3A
Entrez ID		55181	23049
HPRD ID		08551	06123
Ensembl ID		ENSG00000167447	ENSG00000157106
Uniprot IDs		Q8ND04	Q96Q15
PDB IDs
Enriched GO Terms of Interacting Partners?
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