THAP1 and ABCF3

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		THAP1	ABCF3
Description		THAP domain containing 1	ATP binding cassette subfamily F member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle	Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding	Protein Binding ATP Binding ATPase Activity Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle	Defense Response To Virus
Pathways
Drugs
Diseases		Primary torsion dystonia (PTD)
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240)	Major depressive disorder ( 22472876)
Interacting Genes		65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408	20 interacting genes: ACIN1 CCDC33 DLEU1 DNALI1 FBXO7 FCHSD2 HIRIP3 LAMTOR1 MDFI MOCS2 NOA1 PSME3 RBPMS SLC35E1 SPP1 TBPL1 THAP1 TOE1 TRIM14 TRIM27
Entrez ID		55145	55324
HPRD ID		15496	12404
Ensembl ID		ENSG00000131931	ENSG00000161204
Uniprot IDs		Q9NVV9	A0A0S2Z5L1 Q9NUQ8
PDB IDs		2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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