MAGOHB and ZNF250

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAGOHB	ZNF250
Description		mago homolog B, exon junction complex subunit	zinc finger protein 250
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Exon-exon Junction Complex Neuronal Cell Body U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Nucleus
	Molecular Function	RNA Binding Protein Binding	DNA Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	Regulation Of Transcription, DNA-templated
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Generic Transcription Pathway
Drugs
Diseases
GWAS			Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		21 interacting genes: AMOTL2 CALCOCO2 CCDC102B DVL2 GOLGA2 HMG20A IKZF3 KRT40 MID2 RBM8A RBMX REL RUNDC3A TCF4 TERF2 TERF2IP TLE5 TRIM42 YWHAG ZNF250 ZNF398	47 interacting genes: BEGAIN CARD9 CCDC102B CCDC136 CCDC85B CDCA7L CEP44 DPPA2 DVL2 FAM124A GMCL1 GNPTAB GOLGA2 HEXIM2 HOOK1 HOOK2 KASH5 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 LDOC1 LZTS2 MAGOHB MID2 MTUS2 NINL PLEKHF2 PRPF31 SSX2IP SYNE4 TFF1 TMCC2 TNNT1 TNS2 TRAF1 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB8A ZC4H2 ZNF165 ZNF175 ZNF460 ZNF473
Entrez ID		55110	58500
HPRD ID		08544	15758
Ensembl ID		ENSG00000111196	ENSG00000196150
Uniprot IDs		A0A023T6R1 F5H6P7 Q96A72	B3KNS9 P15622
PDB IDs		5XJC 5YZG 6ICZ 6QDV
Enriched GO Terms of Interacting Partners?
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