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HPF1 and H1-5
Number of citations of the paper that reports this interaction (PubMedID
27067600
)
44
Data Source:
BioGRID
(pull down)
HPF1
H1-5
Description
histone PARylation factor 1
H1.5 linker histone, cluster member
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleosome
Nuclear Chromatin
Nucleus
Nuclear Euchromatin
Nuclear Heterochromatin
Molecular Function
Protein Binding
Zinc Ion Binding
Histone Binding
Poly-ADP-D-ribose Binding
Double-stranded DNA Binding
RNA Binding
Protein Binding
Chromatin DNA Binding
Nucleosomal DNA Binding
Histone Deacetylase Binding
Biological Process
Cellular Response To DNA Damage Stimulus
Regulation Of Protein ADP-ribosylation
Peptidyl-serine ADP-ribosylation
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Nucleosome Assembly
Regulation Of Transcription, DNA-templated
Muscle Organ Development
Nucleosome Positioning
Chromosome Condensation
Positive Regulation Of Cell Growth
Negative Regulation Of Chromatin Silencing
Negative Regulation Of DNA Recombination
Protein Stabilization
Positive Regulation Of Histone H3-K9 Methylation
Establishment Of Protein Localization To Chromatin
Pathways
Apoptosis induced DNA fragmentation
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes
15 interacting genes:
EIF6
FBXO7
H1-0
H1-5
H2BC4
H3-3A
H3-4
H3C1
HMGA1
HMGB1
HMGN1
HMGN2
HMGN4
PARP1
PARP2
30 interacting genes:
CBX5
CCNA1
CCNA2
CCNB1
CCNE1
CDK1
CDK2
CDK5
CDKN1A
CDKN1B
EHMT2
HPF1
IRAK4
KAT2A
KAT2B
L3MBTL1
LOX
MELK
MLLT1
NSD1
PARP1
PARP2
PRKCA
PRKCB
PRKCD
PRKCZ
RIPK3
RPS6KA5
SERPINH1
SIRT1
Entrez ID
54969
3009
HPRD ID
07924
00821
Ensembl ID
ENSG00000056050
ENSG00000184357
Uniprot IDs
Q9NWY4
P16401
PDB IDs
2FE2
2RHI
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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