NSD3 and MLLT6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NSD3	MLLT6
Description		nuclear receptor binding SET domain protein 3	MLLT6, PHD finger containing
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific)	Protein Binding Nucleosome Binding Histone Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Histone H3-K36 Methylation Histone Methylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Histone H3-K36 Trimethylation	Regulation Of Transcription, DNA-templated Positive Regulation Of Sodium Ion Transport Negative Regulation Of Urine Volume Renal Sodium Excretion Renal Potassium Excretion Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K79 Methylation
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Interacting Genes		40 interacting genes: AKT1 ATM BCAR3 CASP8 CBLC CBX3 CBX5 CDKN2A CHEK2 DAXX DOCK7 ESR1 ETV3 FGFR4 GLIS2 GLYR1 H1-1 H3-5 H3C1 H4C1 HOXC4 MLLT6 MNDA MYC NFIC PAX2 PPM1D RB1CC1 SEPTIN6 SLU7 SOX3 SOX4 SPAG8 STAC3 TCF3 TEAD2 TERT TGFB1 UBE2I ZNF557	19 interacting genes: APP CASK CEBPE CEBPG CEP44 CRX ENOX2 IKBKG KRTAP10-8 MED15 MEOX2 NSD3 SPRY2 TCF12 TCF4 UBE2G2 UBQLN1 UBQLN4 ZBTB22
Entrez ID		54904	4302
HPRD ID		06155	08978
Ensembl ID		ENSG00000147548	ENSG00000275023
Uniprot IDs		Q9BZ95	P55198
PDB IDs		2DAQ 2NCZ 2ND1 4GND 4GNE 4GNF 4GNG 4RXJ 5UPD 6CEN 6G24 6G25 6G27 6G29 6G2B 6G2C 6G2E 6G2F 6G2O 6G3P 6G3T
Enriched GO Terms of Interacting Partners?
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