NCAPG2 and TAL1

Number of citations of the paper that reports this interaction (PubMedID 14729962)
6

Data Source:
HPRD (two hybrid)

		NCAPG2	TAL1
Description		non-SMC condensin II complex subunit G2	TAL bHLH transcription factor 1, erythroid differentiation factor
Image		No pdb structure
GO Annotations	Cellular Component	Condensin Complex Nucleoplasm Membrane Nuclear Speck	Histone Deacetylase Complex Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Lsd1/2 Complex
	Molecular Function	Protein Binding Methylated Histone Binding BHLH Transcription Factor Binding Molecular Function Regulator	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding Protein Dimerization Activity E-box Binding
	Biological Process	Inner Cell Mass Cell Proliferation Transcription By RNA Polymerase II Cell Cycle Erythrocyte Differentiation Chromosome Condensation Negative Regulation Of Erythrocyte Differentiation Cell Division Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Signaling Receptor Activity	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Locomotory Behavior Spinal Cord Association Neuron Differentiation Hemopoiesis Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Positive Regulation Of Protein Complex Assembly Embryonic Hemopoiesis Megakaryocyte Development Regulation Of Cell Proliferation Erythrocyte Maturation Cell Fate Commitment Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Chromatin Assembly Or Disassembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Division Astrocyte Fate Commitment Definitive Hemopoiesis Hemangioblast Cell Differentiation Hematopoietic Stem Cell Differentiation Regulation Of Mast Cell Differentiation Positive Regulation Of Protein Tyrosine Kinase Activity Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Stem Cell Population Maintenance Positive Regulation Of Signaling Receptor Activity
Pathways		Condensation of Prophase Chromosomes	RUNX1 regulates transcription of genes involved in differentiation of HSCs Transcriptional regulation of granulopoiesis
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Metabolite levels ( 23823483) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Number of sexual partners ( 30643258) Risk-taking tendency (4-domain principal component model) ( 30643258) Testicular germ cell tumor ( 28604732)	Body mass index ( 25673413) Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular volume ( 27863252)
Interacting Genes		1 interacting genes: TAL1	24 interacting genes: CHD3 DRG1 ELSPBP1 EP300 GATA1 GATA2 GATA3 HDAC1 HOXB9 KAT2B KDM1A LMO1 LMO2 MAPK3 NCAPG2 PRKCQ SIN3A SKP2 SP1 STOML2 STUB1 TCF3 TCF4 ZHX1
Entrez ID		54892	6886
HPRD ID		10539	01753
Ensembl ID		ENSG00000146918	ENSG00000162367
Uniprot IDs		B3KRQ2 Q86XI2	P17542 Q16509
PDB IDs			2YPA 2YPB
Enriched GO Terms of Interacting Partners?
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