QRICH1 and HSPB8

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		QRICH1	HSPB8
Description		glutamine rich 1	heat shock protein family B (small) member 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Intracellular Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Biological_process Regulation Of Cell Morphogenesis	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy
Pathways			HSF1-dependent transactivation
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Coronary artery disease ( 29212778) Crohn's disease ( 28067908) General factor of neuroticism ( 30867560) Inflammatory bowel disease ( 28067908) Resting heart rate ( 27798624) Ulcerative colitis ( 28067908)	Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		17 interacting genes: ATF7IP ATXN1 CRX FHL3 GMCL1 HSFY1 HSPB8 MEOX1 NFIX NLK POGZ PUF60 RBM17 SEPHS1 SIAH1 TRAF1 ZDHHC17	13 interacting genes: BAG3 CRYAB CSNK2A1 DUSP12 HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 PRKCA QRICH1 SNCA
Entrez ID		54870	26353
HPRD ID		13372	06420
Ensembl ID		ENSG00000198218	ENSG00000152137
Uniprot IDs		A1L3Z9 Q2TAL8	Q9UJY1
PDB IDs
Enriched GO Terms of Interacting Partners?
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