SYTL2 and RAB27B

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SYTL2	RAB27B
Description		synaptotagmin like 2	RAB27B, member RAS oncogene family
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Melanosome Exocytic Vesicle	Cell Late Endosome Golgi Apparatus Golgi Stack Plasma Membrane Endomembrane System Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Rab GTPase Binding Phosphatase Binding Neurexin Family Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Negative Regulation Of Phosphatase Activity Vesicle-mediated Transport Positive Regulation Of Mucus Secretion Protein Localization To Plasma Membrane	Platelet Degranulation Intracellular Protein Transport Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways			Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Pallidum volume ( 31530798)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		6 interacting genes: FBXO25 MTERF1 NRXN1 PPP1CA RAB27A RAB27B	8 interacting genes: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		54843	5874
HPRD ID		10260	04846
Ensembl ID		ENSG00000137501	ENSG00000041353
Uniprot IDs		A0A0U1RR07 Q9HCH5	O00194
PDB IDs		3BC1	2F7S
Enriched GO Terms of Interacting Partners?
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