ERCC6L and LMO4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ERCC6L	LMO4
Description		ERCC excision repair 6 like, spindle assembly checkpoint helicase	LIM domain only 4
Image
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Cytosol Membrane	Transcription Factor Complex Cell Leading Edge
	Molecular Function	DNA Binding DNA Helicase Activity Protein Binding ATP Binding DNA Translocase Activity	Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	Cell Cycle DNA Duplex Unwinding Cell Division	Neural Tube Closure Ventricular Septum Development Transcription By RNA Polymerase II Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Regulation Of Cell Migration Negative Regulation Of Protein Complex Assembly Positive Regulation Of Kinase Activity Regulation Of Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Thymus Development Regulation Of Cell Activation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Breast cancer ( 27354352) Eosinophil counts ( 29403010) Gait rhythm ( 26219847) Glaucoma (primary open-angle) ( 29891935) Photic sneeze reflex ( 27182965) Prostate-specific antigen levels ( 28139693) Response to TNF antagonist treatment ( 18615156) Resting heart rate ( 27798624) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		3 interacting genes: HTT LMO4 ZDHHC17	53 interacting genes: AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TLE5 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675
Entrez ID		54821	8543
HPRD ID		10974	09122
Ensembl ID		ENSG00000186871	ENSG00000143013
Uniprot IDs		Q2NKX8	P61968
PDB IDs		5JNO	2L4Z
Enriched GO Terms of Interacting Partners?
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