FBLIM1 and TRIM15

Number of citations of the paper that reports this interaction (PubMedID 25450970)
15

Data Source:
BioGRID (protein complementation assay)

		FBLIM1	TRIM15
Description		filamin binding LIM protein 1	tripartite motif containing 15
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Stress Fiber Cytosol Focal Adhesion Cell Junction
	Molecular Function	Protein Binding Filamin Binding Metal Ion Binding	Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Cell Shape Regulation Of Integrin Activation Cell Junction Assembly Cell-cell Adhesion	Mesodermal Cell Fate Determination Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of RIG-I Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Viral Release From Host Cell
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Cardiac Troponin-T levels ( 23247143) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549)	Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Neurociticism ( 29500382) Neuroticism ( 29255261)
Interacting Genes		7 interacting genes: CUTA FERMT2 FLNA FLNB H3C1 LMO3 TRIM15	36 interacting genes: ACD ACTB AXIN1 CFL1 CORO1B CTTN EHMT1 FAM151B FAM161A FBLIM1 FERMT2 FERMT3 GAB1 GTF2E1 IRF5 KEAP1 MED7 MSN MYBL2 NEXN PFN1 PRNP PTK2 PXN RABGEF1 ROCK1 SHC1 SNW1 SYK TAF9B TINF2 TRIM8 UBE2U VASP VCL VIM
Entrez ID		54751	89870
HPRD ID		09669	15551
Ensembl ID		ENSG00000162458	ENSG00000204610
Uniprot IDs		Q8WUP2	Q5SRL0 Q9C019
PDB IDs		2K9U 2W0P 4P3W
Enriched GO Terms of Interacting Partners?
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