KIF1A and RFX6

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		KIF1A	RFX6
Description		kinesin family member 1A	regulatory factor X6
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Synaptic Vesicle Axon Dendrite Neuron Projection Neuronal Cell Body Extrinsic Component Of Neuronal Dense Core Vesicle Membrane Postsynapse Neuronal Dense Core Vesicle Axon Cytoplasm	Nuclear Chromatin Nucleus
	Molecular Function	Motor Activity Microtubule Motor Activity ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Identical Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	Microtubule-based Movement Anterograde Axonal Transport Vesicle-mediated Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Protein Transport Along Microtubule Dense Core Granule Cytoskeletal Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport	Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Pancreatic D Cell Differentiation Regulation Of Transcription By RNA Polymerase II Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Glucose Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Secretion Pancreatic Epsilon Cell Differentiation
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Regulation of gene expression in beta cells
Drugs		Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Height ( 31562340) Response to placebo treatment in childhood asthma (FVC change) ( 31557306)	Chronic obstructive pulmonary disease ( 30804561) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 27841878) Height ( 31562340) Inflammatory bowel disease ( 27569725) Lung cancer ( 28604730) Neutrophil percentage of granulocytes ( 27863252) Offspring birth weight ( 31043758) Prostate cancer ( 20676098 31562322 26443449) Serum total protein level ( 29403010)
Interacting Genes		26 interacting genes: ADAMTSL4 AR ESR1 FXR2 GIT1 MDFI MED1 MID2 MKRN3 MTUS2 NOTCH2NLA PLSCR1 PPARG PSMA3 RBPMS RFX6 RGS20 RNF31 RXRA SP1 SPRY2 TNS2 TRAF1 TRIM27 TRIP6 TSPOAP1	27 interacting genes: ARNT2 CATSPER1 CCNK CYFIP1 DGCR6 DTX2 ESR2 FHL3 FRS3 HGS KIF1A LMO3 NEDD9 PITX1 PLEKHN1 PRKAA1 PRKAA2 RFX2 RFX3 RIPK3 SNRPB SNRPC SS18L1 STK16 TLE5 VPS37C ZNF688
Entrez ID		547	222546
HPRD ID		03156	11490
Ensembl ID		ENSG00000130294	ENSG00000185002
Uniprot IDs		A0A3B3IT28 A0A3B3ITE5 A0A3B3IU40 Q12756	Q8HWS3
PDB IDs		4EGX 4EJQ 4UXO 4UXP 4UXR 4UXS
Enriched GO Terms of Interacting Partners?
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