Description |
peroxisome proliferator activated receptor gamma |
ubiquitin C |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Alpha-Linolenic Acid
- Icosapent
- Troglitazone
- Mesalazine
- Valproic Acid
- Indomethacin
- Rosiglitazone
- Fenoprofen
- Nateglinide
- Sulfasalazine
- Repaglinide
- Telmisartan
- Balsalazide
- Fenofibrate
- Ibuprofen
- Glipizide
- Amiodarone
- Pioglitazone
- Mitiglinide
- Bezafibrate
- Flufenamic Acid
- Resveratrol
- Phthalic Acid
- Capric acid
- Doconexent
- Oleic Acid
- (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid
- 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- Reglixane
- Elafibranor
- T131
- CLX-0921
- (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
- (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid
- 2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- (4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid
- (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid
- (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
- (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
- (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
- difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron
- (2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID
- 3-(5-methoxy-1H-indol-3-yl)propanoic acid
- Indeglitazar
- (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
- 2-chloro-5-nitro-N-phenylbenzamide
- (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
- 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid
- 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
- (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid
- 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE
- Triclosan
- (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid
- Aleglitazar
- Clinofibrate
- Lobeglitazone
- Ciglitazone
- Dexibuprofen
- Omega-3 fatty acids
- Curcumin
- Arhalofenate
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Diseases |
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GWAS |
- Arterial stiffness index ( 31235810)
- Body mass index ( 28892062 25673413 29273807)
- Cholesterol, total ( 25961943)
- Drug-induced liver injury ( 22968431)
- Endometrial cancer ( 30093612)
- Endometrial cancer (endometrioid histology) ( 30093612)
- Eosinophil counts ( 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 27863252)
- Fasting blood insulin ( 25631608)
- Fasting blood insulin (BMI interaction) ( 22581228)
- Fasting blood insulin adjusted for BMI ( 25625282)
- Gut microbiota (functional units) ( 27694959)
- HDL cholesterol ( 30275531)
- Heel bone mineral density ( 30598549)
- Hematocrit ( 27863252)
- Hemoglobin concentration ( 27863252)
- High density lipoprotein cholesterol levels ( 29403010)
- Hip circumference adjusted for BMI ( 25673412)
- Idiopathic osteonecrosis of the femoral head ( 31135556)
- LDL cholesterol ( 25961943)
- LDL cholesterol levels ( 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Medication use (drugs used in diabetes) ( 31015401)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Medication use (thyroid preparations) ( 31015401)
- Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI) ( 27416945)
- Neutrophil percentage of granulocytes ( 27863252)
- Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
- Platelet count ( 29403010)
- Potassium levels ( 29403010)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Systemic lupus erythematosus ( 28714469)
- Type 2 diabetes ( 22885922 18372903 24509480 30054458 29358691 30297969 29632382 31118516 20581827 17463246 30718926 17463248 17463249 28869590)
- Type 2 diabetes (adjusted for BMI) ( 29632382)
- Waist circumference ( 31453325)
- Waist circumference variance ( 31453325)
- Waist-hip ratio ( 25673412)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
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- HDL cholesterol levels ( 30698716)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- High density lipoprotein cholesterol levels ( 29403010)
- Total cholesterol levels ( 29403010)
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Interacting Genes |
106 interacting genes:
ALOX15B
ANP32A
APP
BCAS2
BRD8
CDC34
CDK5
CEP350
CNOT1
COPS5
CREBBP
DNTTIP2
EDF1
EGFR
FABP1
FHOD1
FOXO1
GADD45B
GADD45G
GRIP1
HDAC1
HDAC3
HDAC4
HELZ2
HMGA1
IGFBP3
IKBKB
JAZF1
JMJD1C
JUN
JUND
KAT2A
KAT5
KCTD13
KIF11
KIF1A
KLF5
LMO4
LRIF1
MAFF
MAP2K1
MAPK1
MAPK8
MED1
MED24
MFHAS1
MIF4GD
MSX2
MUC1
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NFE2L2
NFE2L3
NFKB1
NFKBIB
NR0B1
NR0B2
NR2E3
NR4A1
NR4A2
NRIP1
NSD1
PAK4
PDIA2
PHB2
PML
POU1F1
PPARGC1A
PPM1B
PRKCA
RAD54L2
RANBP9
RB1
RELA
ROBO4
RXRA
RXRB
RXRG
SERPINH1
SFPQ
SIRT1
SMARCD3
STAT6
STUB1
SVIL
SYT1
TFAP2A
TNP1
TRIM24
TRIP4
UBC
UBE2I
USP7
VDR
ZBTB20
ZBTB3
ZBTB5
ZBTB9
ZNF496
ZNHIT3
ZSCAN1
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638 interacting genes:
ABCB7
ABL1
ABRAXAS1
ABRAXAS2
ACTA1
ACTC1
ACTL8
ADH7
ADRM1
AGO2
AGRN
AGTPBP1
ALG1
AMPH
ANAPC1
ANAPC11
ANAPC7
ANGPTL3
ANKRD13A
ANKRD13B
ANKRD13D
ANKRD30A
ANKS1A
ANKS1B
ANP32E
ANTXR1
AP2A1
AP2A2
AP2B1
AP2M1
AP2S1
AREL1
ARIH1
ARIH2
ARMC1
ARRB2
ASB11
ASB2
ASCC2
ASCC3
ASXL1
ASXL2
ATG16L1
ATP5PD
ATXN3
ATXN3L
ATXN7L3
BABAM1
BABAM2
BAP1
BARD1
BARX1
BCAS2
BCR
BECN1
BFAR
BIN1
BIRC2
BIRC3
BRAP
BRCA1
BRCC3
BRF1
BSG
BTD
BTRC
C8orf34
CAPN15
CASP8
CAVIN1
CAVIN3
CBL
CBLB
CBLC
CBR1
CBR3
CCDC50
CCDC92
CD2
CD2AP
CDC20
CDC34
CDC42
CDC45
CDH2
CDH22
CDK17
CDY1B
CENPE
CEP164
CEP192
CEP55
CEP83
CFAP36
CHD3
CHGA
CHP1
CHUK
CLN8
CLU
COL1A1
COPB1
CPT1A
CRACD
CTBP2
CTRC
CUEDC1
CUEDC2
CUL1
CUL2
CUL3
CUL4A
CUL4B
CUL5
CYLD
DAXX
DAZAP2
DCUN1D1
DDI1
DDI2
DDX19B
DDX58
DECR2
DENR
DESI1
DHX15
DLGAP4
DMBX1
DNAH7
DNAJB2
DNASE2B
DOCK6
DPH1
DPY30
ECE2
EFS
EIF3A
ELL
ELOC
ELOVL5
EP300
EPN1
EPN2
EPS15
EPS15L1
ERCC6
ERGIC2
ERVK13-1
EXOSC8
FAAP20
FAF1
FAN1
FAT1
FBH1
FBXL15
FBXO44
FCHO2
FETUB
FGA
FIS1
FLOT1
FLOT2
FSHR
GARNL3
GBF1
GFPT2
GGA1
GGA3
GLG1
GRB2
GTF2H1
GTF2I
GTF2IRD1
H2AC18
H2AC20
H2BC21
HACD1
HACD2
HDAC5
HDAC6
HECW1
HERC1
HERC2
HERC3
HERC4
HGS
HLTF
HMGN2
HNRNPM
HPDL
HRNR
HSD17B11
HSPA5
HSPA8
HSPG2
HUWE1
HYDIN
HYDIN2
IDE
IGF1R
IKBKB
IKBKG
ILF3
ING1
INPPL1
IRS1
ISX
ITCH
ITGAV
ITSN2
JOSD1
JOSD2
JUN
KCTD7
KDM3B
KEAP1
KEL
KHDRBS1
KIAA0586
KLHL11
KLHL13
KLHL7
LACTB
LAMA1
LAMA5
LAMB1
LAMC1
LAPTM5
LARP1B
LIMA1
LINC02593
LNPK
LTF
LTN1
MACF1
MAD1L1
MAP2K4
MAP3K7
MAP4
MAPRE2
MARCHF6
MARCHF7
MBOAT7
MDM2
MDM4
MDN1
MED15
MINDY1
MINDY2
MINDY3
MINDY4
MORC3
MRPL37
MTERF4
MUC16
MUC5B
MUL1
MVP
MYCBP
MYL1
MYL3
MYO6
N4BP1
NAA10
NAT10
NBPF1
NBPF10
NBPF11
NBPF12
NBPF14
NBPF8
NBPF9
NBR1
NCK2
NCKAP5L
NCOA6
NDC1
NDUFB9
NDUFS8
NEDD4
NEDD4L
NEK8
NEURL3
NFIA
NFX1
NPLOC4
NPM1
NPTN
NSFL1C
NSMCE1
NT5C1B
NXPH4
OGT
OPA3
OPRM1
OPTN
OR7G3
OSBPL8
OTOG
OTUB1
OTUB2
OTUD1
OTUD3
OTUD4
OTUD5
OTUD6A
OTUD6B
OTUD7A
OTUD7B
P4HTM
PABPC4
PARP10
PCBP2
PCMTD1
PDCD6IP
PDE12
PDS5A
PELI1
PHF20L1
PHPT1
PIK3C2B
PINK1
PLAA
PLEC
PMS2
POLI
POLR2C
POP5
PPA1
PPARG
PPARGC1A
PPL
PPM1D
PRAME
PRDX4
PRKCI
PRKN
PRPF8
PRR23B
PSMA6
PSMC1
PSMC2
PSMC3
PSMC4
PSMC5
PSMC6
PSMD1
PSMD10
PSMD11
PSMD12
PSMD13
PSMD2
PSMD3
PSMD4
PSMD5
PSMD6
PSMD7
PSMD8
PTH1R
PTOV1
PTPN2
PTPN23
PUS7L
R3HDM4
RABEP1
RABEP2
RABGEF1
RAC1
RAD18
RAD23A
RAD23B
RAG1
RASAL2
RB1CC1
RBCK1
RC3H2
RCHY1
RECQL
REV1
RFC1
RGPD3
RGS2
RIOK3
RNF11
RNF111
RNF114
RNF115
RNF123
RNF125
RNF126
RNF130
RNF144A
RNF144B
RNF145
RNF151
RNF165
RNF181
RNF182
RNF2
RNF216
RNF31
RNF38
RNF4
RNF5
RNF8
RPL12
RPL7L1
RPN1
RPS3
RTL8B
RTL8C
RTTN
RYBP
SBF2
SCD
SDC4
SDCBP
SDF2
SDK1
SEMA3F
SEPTIN1
SEPTIN7P2
SFPQ
SGK1
SGPP1
SH3KBP1
SHARPIN
SLC27A2
SLC38A5
SLC5A6
SLIT2
SLX4
SMAD1
SMURF1
SMURF2
SMYD4
SNCA
SNRNP25
SNRPA
SNTB2
SNTG1
SOCS5
SPAG1
SPECC1L
SPRTN
SQSTM1
SRPRB
STAM
STAM2
STAMBP
STUB1
SUN5
SYNE2
TAB1
TAB2
TAC3
TAPBP
TAX1BP1
TBC1D15
TBC1D5
TBXAS1
TCAF1
TCEAL1
TCHH
TCOF1
TCP10L3
THG1L
TIAM1
TMEM120A
TMEM132A
TMEM160
TMEM189
TMEM201
TMEM223
TNFAIP3
TNFAIP6
TNIP1
TNIP2
TNIP3
TNRC6A
TOLLIP
TOM1
TOM1L1
TOM1L2
TOPORS
TOR1AIP2
TRAF2
TRAF3IP2
TRAF5
TRAF6
TRAFD1
TRAM1
TRIM17
TRIM21
TRIM23
TRIM25
TRIM32
TRIM36
TRIM39
TRIM5
TRIP12
TRIP4
TSG101
TSTA3
TTC28
TTC36
TTF2
TUBA3C
TUBA3D
TUBGCP2
UBA1
UBA2
UBA6
UBAC1
UBAC2
UBAP1
UBASH3A
UBASH3B
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2G2
UBE2J2
UBE2K
UBE2L3
UBE2N
UBE2O
UBE2Q1
UBE2Q2
UBE2R2
UBE2S
UBE2V1
UBE2V2
UBE3A
UBFD1
UBL7
UBQLN1
UBQLN2
UBQLN4
UBR4
UBR5
UBXN1
UBXN6
UCHL1
UCHL5
UEVLD
UFD1
UIMC1
ULK1
UNC79
UNC93B3
USP1
USP10
USP11
USP12
USP13
USP14
USP15
USP16
USP19
USP20
USP21
USP22
USP24
USP25
USP27X
USP28
USP3
USP30
USP31
USP32
USP33
USP34
USP35
USP36
USP37
USP38
USP4
USP40
USP42
USP45
USP46
USP47
USP48
USP53
USP54
USP6
USP7
USP8
USP9X
USP9Y
VCP
VCPIP1
VPS28
VPS36
VPS37A
VPS37C
VPS50
WARS1
WBP2
WDR33
WDR48
WFDC8
WRNIP1
WWP1
WWP2
XIAP
XPNPEP1
XRCC5
XRCC6
YAF2
YARS2
YIPF5
YOD1
YWHAB
YWHAG
YWHAZ
ZBTB1
ZC3H12A
ZCWPW2
ZFAND2B
ZFAND3
ZFAND5
ZFAND6
ZFYVE9
ZHX1
ZNF148
ZNF213
ZNF451
ZNF705G
ZNF716
ZNF792
ZNRF1
ZNRF2
ZRANB1
ZUP1
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Entrez ID |
5468 |
7316 |
HPRD ID |
03288 |
07038 |
Ensembl ID |
ENSG00000132170
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ENSG00000150991
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Uniprot IDs |
A0A494C1F9
D2KUA6
E9PFX5
P37231
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P0CG48
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PDB IDs |
1FM6
1FM9
1I7I
1K74
1KNU
1NYX
1PRG
1RDT
1WM0
1ZEO
1ZGY
2ATH
2F4B
2FVJ
2G0G
2G0H
2GTK
2HFP
2HWQ
2HWR
2I4J
2I4P
2I4Z
2OM9
2P4Y
2POB
2PRG
2Q59
2Q5P
2Q5S
2Q61
2Q6R
2Q6S
2Q8S
2QMV
2VSR
2VST
2VV0
2VV1
2VV2
2VV3
2VV4
2XKW
2YFE
2ZK0
2ZK1
2ZK2
2ZK3
2ZK4
2ZK5
2ZK6
2ZNO
2ZVT
3ADS
3ADT
3ADU
3ADV
3ADW
3ADX
3AN3
3AN4
3B0Q
3B0R
3B1M
3B3K
3BC5
3CDP
3CDS
3CS8
3CWD
3D6D
3DZU
3DZY
3E00
3ET0
3ET3
3FEJ
3FUR
3G9E
3GBK
3H0A
3HO0
3HOD
3IA6
3K8S
3KMG
3LMP
3NOA
3OSI
3OSW
3PBA
3PO9
3PRG
3QT0
3R5N
3R8A
3R8I
3S9S
3SZ1
3T03
3TY0
3U9Q
3V9T
3V9V
3V9Y
3VJH
3VJI
3VN2
3VSO
3VSP
3WJ4
3WJ5
3WMH
3X1H
3X1I
4A4V
4A4W
4CI5
4E4K
4E4Q
4EM9
4EMA
4F9M
4FGY
4HEE
4JAZ
4JL4
4L96
4L98
4O8F
4OJ4
4PRG
4PVU
4PWL
4R06
4R2U
4R6S
4XLD
4XTA
4XUH
4XUM
4Y29
4YT1
5AZV
5DSH
5DV3
5DV6
5DV8
5DVC
5DWL
5F9B
5GTN
5GTO
5GTP
5HZC
5JI0
5LSG
5TTO
5TWO
5U5L
5UGM
5WQX
5WR0
5WR1
5Y2O
5Y2T
5YCN
5YCP
5Z5S
5Z6S
6AD9
6AN1
6AUG
6AVI
6C1I
6C5Q
6C5T
6D3E
6D8X
6D94
6DBH
6DCU
6DGL
6DGO
6DGP
6DGQ
6DGR
6DH9
6DHA
6E5A
6ENQ
6F2L
6FZF
6FZG
6FZJ
6FZP
6FZY
6ICJ
6IJR
6IJS
6ILQ
6IZM
6IZN
6JQ7
6K0T
6MCZ
6MD0
6MD1
6MD2
6MD4
6MS7
6O67
6O68
|
1C3T
1CMX
1D3Z
1F9J
1FXT
1G6J
1GJZ
1NBF
1OGW
1Q5W
1S1Q
1SIF
1TBE
1UBI
1UBQ
1UD7
1XD3
1XQQ
1YX5
1YX6
1ZGU
1ZO6
2AYO
2BGF
2DEN
2FUH
2G45
2GBJ
2GBK
2GBM
2GBN
2GBR
2GMI
2HTH
2IBI
2J7Q
2JF5
2JRI
2JY6
2JZZ
2K25
2K6D
2K8B
2K8C
2KDF
2KHW
2KJH
2KLG
2KN5
2KX0
2L3Z
2LD9
2LVO
2LVP
2LVQ
2LZ6
2MBO
2MBQ
2MCN
2MI8
2MJ5
2MOR
2MRE
2MWS
2N2K
2NR2
2O6V
2OJR
2PE9
2PEA
2RR9
2RU6
2W9N
2WDT
2XEW
2Y5B
2Z59
2ZCB
2ZVN
2ZVO
3A33
3ALB
3AUL
3B08
3B0A
3BY4
3C0R
3DVG
3DVN
3EEC
3EFU
3EHV
3H7P
3H7S
3HM3
3I3T
3IFW
3IHP
3JSV
3JVZ
3JW0
3K9O
3K9P
3KVF
3KW5
3LDZ
3MHS
3MTN
3N30
3N32
3N3K
3NS8
3O65
3OFI
3OJ3
3OJ4
3ONS
3PRM
3PT2
3PTF
3Q3F
3RUL
3TMP
3U30
3UGB
3V6C
3V6E
3VFK
3VUW
3VUX
3VUY
3WXE
3WXF
3ZLZ
3ZNH
3ZNI
3ZNZ
4AP4
4AUQ
4BOS
4BOZ
4BVU
4DDG
4DDI
4DHJ
4DHZ
4FJV
4HK2
4HXD
4I6L
4I6N
4IG7
4IUM
4JQW
4K1R
4K7S
4K7U
4K7W
4KSK
4KSL
4LCD
4LDT
4MDK
4MM3
4MSM
4MSQ
4NQK
4UN2
4V3K
4V3L
4WZP
4XOK
4XOL
4ZQS
5A5B
5AF4
5AF5
5AF6
5AIT
5AIU
5B83
5C7J
5C7M
5E6J
5H07
5NL4
5NLF
5NLI
5NMC
5OE7
5OHV
5OXH
5OXI
5UDH
5WQ4
5ZQ3
5ZQ4
5ZQ5
5ZQ6
5ZQ7
6A43
6A44
6AQR
6B7M
6B7O
6EQI
6N13
6N6R
6NQA
6OI4
6RYA
6S53
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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