PLEKHA5 and SPIRE1

		PLEKHA5	SPIRE1
Description		pleckstrin homology domain containing A5	spire type actin nucleation factor 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Cell Nucleoplasm Cytosol Cytoskeleton Cell Cortex Cytoplasmic Vesicle Membrane Integral Component Of Mitochondrial Outer Membrane Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Actin Binding
	Biological Process	Biological_process Reproductive System Development	Protein Transport Vesicle-mediated Transport Actin Cytoskeleton Organization Actin Filament Polymerization Cleavage Furrow Formation Polar Body Extrusion After Meiotic Divisions Actin Nucleation Intracellular Transport Establishment Of Meiotic Spindle Localization Formin-nucleated Actin Cable Assembly Positive Regulation Of Mitochondrial Fission Positive Regulation Of Double-strand Break Repair
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Thalamus volume ( 31530798)	Carotid plaque burden ( 28282560) Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		36 interacting genes: ADK ARHGEF9 BET1 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 H2AJ KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 RECQL SH3BP5L SOGA1 SPIRE1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	1 interacting genes: PLEKHA5
Entrez ID		54477	56907
HPRD ID		09684	11600
Ensembl ID		ENSG00000052126	ENSG00000134278
Uniprot IDs		A0A024RAY7 Q9HAU0	Q08AE8
PDB IDs		2DKP	2YLE 2YLF 3R7G 3RBW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?